Two distinct pathways of tumorigenesis of adenocarcinomas of the esophagogastric junction, related or unrelated to intestinal metaplasia

It is still uncertain whether intestinal metaplasia (IM) of the esophagogastric junction (EGJ) plays a role in the development of adenocarcinoma of the esophagogastric junction (AEGJ). The purpose of the present study was to clarify the relationship between AEGJ and IM in Japanese patients. Forty‐ei...

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Veröffentlicht in:	Pathology international 2007-06, Vol.57 (6), p.315-321
Hauptverfasser:	Nunobe, Souya, Nakanishi, Yukihiro, Taniguchi, Hirokazu, Sasako, Mitsuru, Sano, Takeshi, Kato, Hoichi, Yamagishi, Hisakazu, Sekine, Shigeki, Shimoda, Tadakazu
Format:	Artikel
Sprache:	eng
Schlagworte:	adenocarcinoma Adenocarcinoma - metabolism Adenocarcinoma - pathology Adenocarcinoma - surgery Adult Aged Aged, 80 and over Barrett Esophagus - metabolism Barrett Esophagus - pathology Biomarkers, Tumor - metabolism Esophageal Neoplasms - metabolism Esophageal Neoplasms - pathology Esophageal Neoplasms - surgery esophagogastric junction Esophagogastric Junction - metabolism Esophagogastric Junction - pathology Esophagogastric Junction - surgery Female Gastric Mucosa - metabolism Gastric Mucosa - pathology gastric/intestinal phenotypic expression Humans intestinal metaplasia Intestinal Mucosa - metabolism Intestinal Mucosa - pathology Lymphatic Metastasis Male Metaplasia - metabolism Metaplasia - pathology Middle Aged Phenotype
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Zusammenfassung:	It is still uncertain whether intestinal metaplasia (IM) of the esophagogastric junction (EGJ) plays a role in the development of adenocarcinoma of the esophagogastric junction (AEGJ). The purpose of the present study was to clarify the relationship between AEGJ and IM in Japanese patients. Forty‐eight AEGJ,
ISSN:	1320-5463 1440-1827
DOI:	10.1111/j.1440-1827.2007.02102.x