Laryngeal solitary fibrous tumour

Solitary fibrous tumours (SFT) are rare neoplasms, with an uncommon laryngeal involvement. Only five cases of laryngeal localization have been described in literature. The following is a case of a 75-year-old man with a supraglottic neoplasm of the larynx; after the biopsy immunohistochemical study...

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Veröffentlicht in:Auris, nasus, larynx nasus, larynx, 2007-09, Vol.34 (3), p.405-408
Hauptverfasser: Stomeo, Francesco, Padovani, Davide, Bozzo, Corrado, Pastore, Antonio
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Sprache:eng
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Zusammenfassung:Solitary fibrous tumours (SFT) are rare neoplasms, with an uncommon laryngeal involvement. Only five cases of laryngeal localization have been described in literature. The following is a case of a 75-year-old man with a supraglottic neoplasm of the larynx; after the biopsy immunohistochemical study demonstrated a strong positivity for vimentin, CD34 and Bcl-2. The neoplasm was consequently classified as a SFT. CO 2 laser surgery of the supraglottic larynx, with a wide excision of the neoplasm, was performed. Twenty-four months on, the patient is alive, well and free of disease. Surgical resection is the treatment of choice for laryngeal SFT, but tumour-free resection margins must be achieved to prevent the possibility of local recurrence. Endoscopic resection by means of the CO 2 laser must be accurately planned with MRI or CT imaging to confirm of this kind of surgery.
ISSN:0385-8146
1879-1476
DOI:10.1016/j.anl.2007.01.001