Asymmetric Assembly of Aromatic Rings To Produce Tetra-ortho-Substituted Axially Chiral Biaryl Phosphorus Compounds

Densely substituted title compounds can be obtained efficiently through an enantioselective [2+2+2] cycloaddition catalyzed by a cationic RhI/H8‐binap complex (see scheme). This method is highly practical in view of the ready access to substrates, mild reaction conditions, operational simplicity, and high catalytic activity. cod=1,5‐cyclooctadiene; H8‐binap=2,2′‐bis(diphenylphosphanyl)‐5,5′,6,6′,7,7′,8,8′‐octahydro‐1,1′‐binaphthyl; Ts=p‐toluenesulfonyl.