Quantification of angiogenesis by the Chalkley method and its prognostic significance in epithelial ovarian cancer

Abstract Aim The aim of the present study was to clarify prognostic role of angiogenesis in epithelial ovarian cancer. Methods Quantification of angiogenesis was performed by the Chalkley method after immunostaining of 175 epithelial ovarian cancer specimens with an antibody against CD34. Results Th...

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Veröffentlicht in:	European journal of cancer (1990) 2007-05, Vol.43 (8), p.1300-1307
Hauptverfasser:	Suhonen, Kirsi A, Anttila, Maarit A, Sillanpää, Sari M, Hämäläinen, Kirsi M, Saarikoski, Seppo V, Juhola, Matti, Kosma, Veli-Matti
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age of Onset Aged Aged, 80 and over Angiogenesis Antigens, CD34 - metabolism Biological and medical sciences CD34 Chalkley Disease-Free Survival Female Hematology, Oncology and Palliative Medicine Humans Immunohistochemistry Medical sciences Middle Aged Neovascularization, Pathologic - metabolism Neovascularization, Pathologic - pathology Ovarian cancer Ovarian Neoplasms - blood supply Ovarian Neoplasms - metabolism Pharmacology. Drug treatments Prognosis Survival Survival Analysis Tumors
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Zusammenfassung:	Abstract Aim The aim of the present study was to clarify prognostic role of angiogenesis in epithelial ovarian cancer. Methods Quantification of angiogenesis was performed by the Chalkley method after immunostaining of 175 epithelial ovarian cancer specimens with an antibody against CD34. Results The Chalkley count was categorised into two groups according to the median value: low
ISSN:	0959-8049 1879-0852
DOI:	10.1016/j.ejca.2007.03.007