Toll-like receptors

Toll-like receptors

Toll-like receptors are a family of transmembrane receptors responsible for recognition and initiation of a response to invading microbes by the immune system. As part of the innate immune system, Toll-like receptors recognise pathogen-associated molecular patterns, highly conserved components that...

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Veröffentlicht in:Journal of biological regulators and homeostatic agents 2008-01, Vol.22 (1), p.17-26
Hauptverfasser: Dasari, P, Nicholson, I C, Zola, H
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Autoimmune Diseases - physiopathology
Humans
Infection - physiopathology
Lymphocytes - physiology
Macrophages - physiology
Models, Molecular
Signal Transduction
Toll-Like Receptors - chemistry
Toll-Like Receptors - immunology
Toll-Like Receptors - physiology
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Beschreibung
Zusammenfassung:Toll-like receptors are a family of transmembrane receptors responsible for recognition and initiation of a response to invading microbes by the immune system. As part of the innate immune system, Toll-like receptors recognise pathogen-associated molecular patterns, highly conserved components that are essential to microbial function. Some of ten toll-like receptors identified in humans are able to recognise several pathogen-associated molecular patterns.
ISSN:0393-974X