Practice and Costs of Red Blood Cell (RBC) Transfusion in an Oncological Unit

Background: Cancer related anemia impairs patient functioning. Red blood cell (RBC) transfusion and erythropoietin (EPO) may relieve fatigue. Cost-effectiveness data have been requested. Patients and Methods: All transfusions administered at the Department of Oncology, University Hospital of North Norway (UNN) in 2005 were analysed, with a total of 118 patients entering the study. A cost of transfusion analysis was added and a sensitivity analysis conducted to clarify robustness. The 118 patients received 613 units of erythrocytes. In 6% of cases, the transfusion was the only cause of a hospital visit. One fourth of patients had bone marrow infiltration and two-thirds had undergone chemotherapy. The mean Hb levels of patients prior to and following transfusion were in the range 8.4-8.8 g/dl and 10.2-10.6 g/dl, respectively; one-third reached a non-anemic level (Hb≥11.0 g/dl). The median time interval between transfusions was three weeks and the annual cost was calculated at €1,069/patient. Conclusion: RBC-transfusion has a low cost.