Aqueous Humor and Serum Concentration of Hydroxyproline in Pseudoexfoliation Syndrome

PURPOSETo determine the concentration of hydroxyproline (Hyp) in aqueous humor and serum samples of patients with and without pseudoexfoliation (PEX). PATIENTS AND METHODSAqueous humor and serum Hyp levels were measured in cataract patients. Patients were divided into PEX and control groups. Samples were obtained from 27 cataract patients with PEX and 25 cataract patients without PEX. Patients had no elevated intraocular pressure or glaucoma. Hyp concentration was determined spectrophotometrically. RESULTSMean Hyp concentration in the PEX aqueous (0.86±0.27 mg/L) and serum (40.8±6.14 mg/L) samples was significantly higher than that measured in the control aqueous (0.56±0.2 mg/L) and serum (34.51±6.82 mg/L) samples, respectively (P