Analysis of Macular Edema after Cataract Surgery in Patients with Diabetes Using Optical Coherence Tomography

Objective To assess the incidence or progression of macular edema (ME) after cataract surgery in diabetic patients using optical coherence tomography (OCT) and correlating this with degree of diabetic retinopathy or other risk factors. Design Prospective cohort study. Participants Fifty diabetic eyes undergoing cataract surgery. Methods Each eye underwent 7-field fundus photography no more than 3 months before surgery. Optical coherence tomography testing was performed within 4 weeks before surgery and at 1- and 3-month postoperative visits. Best-corrected visual acuity (BCVA) was recorded at each visit. Macular edema was defined as an increase of center point thickness on OCT > 30% from preoperative baseline. Main Outcome Measures Changes in foveal thickness and BCVA. Results The incidence of ME on OCT was 22% (95% confidence interval, 13%–35%). The average increase in center point thickness at 1 month for eyes with ME was 202 μm, which resulted in a nearly 1-line loss of vision (0.07 logarithm of the minimum angle of resolution [logMAR] units) compared with eyes without ME gaining >2 lines of vision (0.24 logMAR units) ( P >0.001). Eyes with no diabetic retinopathy developed minimal thickening of 18 μm and 14 μm at 1 and 3 months, respectively, associated with approximately 2 and 3 lines of improved vision, respectively (0.22 and 0.26 logMAR units). Eyes with moderate or severe nonproliferative diabetic retinopathy or proliferative diabetic retinopathy developed thickening of 145 μm and 131 μm at 1 and 3 months, respectively, associated with