Age-related macular degeneration and mortality from cardiovascular disease or stroke

Age-related macular degeneration and mortality from cardiovascular disease or stroke

Background/aims:Age-related macular degeneration (AMD) and vascular disease share similar risk factors. Recent data suggest AMD may independently predict stroke or coronary heart disease. We prospectively assessed the relationship between AMD and risk of stroke- or cardiovascular-related death in an...

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Veröffentlicht in:British journal of ophthalmology 2008-04, Vol.92 (4), p.509-512
Hauptverfasser: Tan, J S L, Wang, J J, Liew, G, Rochtchina, E, Mitchell, P
Format: Artikel
Sprache:eng
Schlagworte:
Age Factors
Aged
Australia - epidemiology
Biological and medical sciences
Cardiovascular disease
Cardiovascular Diseases - complications
Cardiovascular Diseases - mortality
Epidemiologic Methods
Female
Health risk assessment
Heart attacks
Humans
Macular degeneration
Macular Degeneration - complications
Macular Degeneration - mortality
Male
Medical sciences
Middle Aged
Miscellaneous
Mortality
Neurology
Ophthalmology
Prognosis
Retinopathies
Stroke - complications
Stroke - mortality
Vascular diseases and vascular malformations of the nervous system
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Zusammenfassung:Background/aims:Age-related macular degeneration (AMD) and vascular disease share similar risk factors. Recent data suggest AMD may independently predict stroke or coronary heart disease. We prospectively assessed the relationship between AMD and risk of stroke- or cardiovascular-related death in an Australian population.Methods:Of 3654 baseline participants (1992–4) aged 49+ years, 2335 were re-examined after 5 years and 1952 after 10 years. Retinal photographs were graded using the Wisconsin System. History and physical examination provided data on possible risk factors. Deaths and cause of death were confirmed by data linkage with the Australian National Death Index. Risk ratios (RR) were estimated in Cox models.Results:Among persons aged
ISSN:0007-1161
1468-2079
DOI:10.1136/bjo.2007.131706