A TLC bioautographic assay for the detection of nitrofurantoin resistance reversal compound

A simple TLC bioautographic method was developed for detection of antibiotic resistance reversal agents. In this study, the retention factor values of the components of some essential oils not previously shown to have any antibacterial activity were evaluated on nitrofurantoin supplemented agar medi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Analytical technologies in the biomedical and life sciences, 2007-05, Vol.850 (1), p.528-530
Hauptverfasser: Shahverdi, Ahmad R., Abdolpour, Farid, Monsef-Esfahani, Hamid R., Farsam, Hasan
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A simple TLC bioautographic method was developed for detection of antibiotic resistance reversal agents. In this study, the retention factor values of the components of some essential oils not previously shown to have any antibacterial activity were evaluated on nitrofurantoin supplemented agar media. The active component of Artemisia annua, Artemisia dracunculus and Eucalyptus globulus essential oils was piperitone which increased the antibacterial activity of nitrofurantoin against Enterobacter cloacae. Piperitone was not detected in the essential oil of Humulus lupulus and we could not observe any clear areas in this bioautographic method.
ISSN:1570-0232
1873-376X
DOI:10.1016/j.jchromb.2006.11.011