Evaluation of Vulnerable Coronary Plaques and Non-Alcoholic Fatty Liver Disease (NAFLD) by 64-Detector Multislice Computed Tomography (MSCT)

Background Multislice computed tomography (MSCT) permits direct visualization of not only coronary artery stenosis but also the characteristics of plaques in patients with coronary artery disease (CAD). Also, because of its potential to be a novel risk factor for cardiovascular disease, interest in...

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Veröffentlicht in:Circulation Journal 2007, Vol.72(4), pp.618-625
Hauptverfasser: Akabame, Satoshi, Hamaguchi, Masahide, Tomiyasu, Ki-ichiro, Tanaka, Muhei, Kobayashi-Takenaka, Yoshiko, Nakano, Koji, Oda, Yohei, Yoshikawa, Toshikazu
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Sprache:eng
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Zusammenfassung:Background Multislice computed tomography (MSCT) permits direct visualization of not only coronary artery stenosis but also the characteristics of plaques in patients with coronary artery disease (CAD). Also, because of its potential to be a novel risk factor for cardiovascular disease, interest in non-alcoholic fatty liver disease (NAFLD) is increasing. Methods and Results Participants comprised 298 consecutive patients who received MSCT to diagnose CAD. Patients with an alcohol intake exceeding 20 g/day or with a history of known liver disease were excluded from the study. Liver steatosis and 4 coronary artery findings, including remodeling lesions, lipid core plaques, calcified plaques and narrowing of lumen, were assessed. Liver steatosis was evaluated by computed tomography density of the liver and spleen. In the study, NAFLD was defined as having a liver and spleen (L:S) ratio of
ISSN:1346-9843
1347-4820
DOI:10.1253/circj.72.618