Electrically Addressable Cell Immobilization Using Phenylboronic Acid Diazonium Salts

Electrically Addressable Cell Immobilization Using Phenylboronic Acid Diazonium Salts

Holding cells: Individual gold electrodes can be activated by phenylboronic acid diazonium salts for the facile and reversible immobilization of eukaryotic cells (see scheme). This platform provides a simple method for on‐demand release of captured cells (yeast and macrophage) and can be used in sin...

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Veröffentlicht in:Angewandte Chemie (International ed.) 2008-03, Vol.47 (14), p.2631-2634
Hauptverfasser: Polsky, Ronen, Harper, Jason C, Wheeler, David R, Arango, Dulce C, Brozik, Susan M
Format: Artikel
Sprache:eng
Schlagworte:
biosensors
Boronic Acids - chemistry
cell adhesion
diazo compounds
Diazonium Compounds - chemistry
electrochemistry
Electrodes
Electrons
Gold - chemistry
immobilization
Molecular Structure
Saccharomyces cerevisiae
Salts - chemistry
Spectroscopy, Fourier Transform Infrared
Surface Properties
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Beschreibung
Zusammenfassung:Holding cells: Individual gold electrodes can be activated by phenylboronic acid diazonium salts for the facile and reversible immobilization of eukaryotic cells (see scheme). This platform provides a simple method for on‐demand release of captured cells (yeast and macrophage) and can be used in single‐cell or array‐based studies.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200704597