Rapid and Efficient Identification of Bacteria Using Gold-Nanoparticle-Poly(para-phenyleneethynylene) Constructs

Microbiological intelligence: Simple constructs of hydrophobically functionalized gold nanoarticles and a conjugated polymer (poly(para‐phenyleneethynylene, PPE) are able to identify three different strains of E. coli in minutes. The negatively charged bacteria replace the negatively charged conjuga...

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Veröffentlicht in:Angewandte Chemie (International ed.) 2008-03, Vol.47 (14), p.2590-2594
Hauptverfasser: Phillips, Ronnie L, Miranda, Oscar R, You, Chang-Cheng, Rotello, Vincent M, Bunz, Uwe H.F
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container_end_page 2594
container_issue 14
container_start_page 2590
container_title Angewandte Chemie (International ed.)
container_volume 47
creator Phillips, Ronnie L
Miranda, Oscar R
You, Chang-Cheng
Rotello, Vincent M
Bunz, Uwe H.F
description Microbiological intelligence: Simple constructs of hydrophobically functionalized gold nanoarticles and a conjugated polymer (poly(para‐phenyleneethynylene, PPE) are able to identify three different strains of E. coli in minutes. The negatively charged bacteria replace the negatively charged conjugated polymers from the positively charged gold nanoparticles (see scheme), differentially restoring the polymer fluorescence.
doi_str_mv 10.1002/anie.200703369
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subjects Alkynes - chemistry
bacteria
Bacteria - chemistry
Bacteria - classification
Bacteria - isolation & purification
bioanalysis
Biosensing Techniques - instrumentation
Biosensing Techniques - methods
biosensors
conjugated polymers
Ethers - chemistry
Fluorescence
Gold - chemistry
gold nanoparticles
Metal Nanoparticles - chemistry
Molecular Structure
Time Factors
title Rapid and Efficient Identification of Bacteria Using Gold-Nanoparticle-Poly(para-phenyleneethynylene) Constructs
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