Rapid and Efficient Identification of Bacteria Using Gold-Nanoparticle-Poly(para-phenyleneethynylene) Constructs

Microbiological intelligence: Simple constructs of hydrophobically functionalized gold nanoarticles and a conjugated polymer (poly(para‐phenyleneethynylene, PPE) are able to identify three different strains of E. coli in minutes. The negatively charged bacteria replace the negatively charged conjuga...

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Veröffentlicht in:	Angewandte Chemie (International ed.) 2008-03, Vol.47 (14), p.2590-2594
Hauptverfasser:	Phillips, Ronnie L, Miranda, Oscar R, You, Chang-Cheng, Rotello, Vincent M, Bunz, Uwe H.F
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkynes - chemistry bacteria Bacteria - chemistry Bacteria - classification Bacteria - isolation & purification bioanalysis Biosensing Techniques - instrumentation Biosensing Techniques - methods biosensors conjugated polymers Ethers - chemistry Fluorescence Gold - chemistry gold nanoparticles Metal Nanoparticles - chemistry Molecular Structure Time Factors
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Zusammenfassung:	Microbiological intelligence: Simple constructs of hydrophobically functionalized gold nanoarticles and a conjugated polymer (poly(para‐phenyleneethynylene, PPE) are able to identify three different strains of E. coli in minutes. The negatively charged bacteria replace the negatively charged conjugated polymers from the positively charged gold nanoparticles (see scheme), differentially restoring the polymer fluorescence.
ISSN:	1433-7851 1521-3773
DOI:	10.1002/anie.200703369