Estrogen receptor α CA dinucleotide repeat polymorphism is associated with rate of bone loss in perimenopausal women and bone mineral density and risk of osteoporotic fractures in postmenopausal women

Estrogen receptor α CA dinucleotide repeat polymorphism is associated with rate of bone loss in perimenopausal women and bone mineral density and risk of osteoporotic fractures in postmenopausal women

Summary The association between a newly identified CA repeat polymorphism of the estrogen receptor alpha gene (ESR1) with osteoporosis was investigated. Postmenopausal women with

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Bibliographische Detailangaben
Veröffentlicht in:Osteoporosis international 2008-04, Vol.19 (4), p.571-579
Hauptverfasser: Lai, B. M. H., Cheung, C. L., Luk, K. D. K., Kung, A. W. C.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Biological and medical sciences
Bone Density - genetics
Dinucleotide Repeats - genetics
Diseases of the osteoarticular system
Endocrinology
Estrogen Receptor alpha - deficiency
Estrogen Receptor alpha - genetics
Female
Fractures, Bone - prevention & control
Genotype
Humans
Injuries of the limb. Injuries of the spine
Investigative techniques, diagnostic techniques (general aspects)
Logistic Models
Medical sciences
Medicine
Medicine & Public Health
Menopause
Middle Aged
Original Article
Orthopedics
Osteoarticular system. Muscles
Osteoporosis, Postmenopausal - physiopathology
Osteoporosis. Osteomalacia. Paget disease
Polymorphism, Genetic - genetics
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Rheumatology
Risk Factors
Traumas. Diseases due to physical agents
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Beschreibung
Zusammenfassung:Summary The association between a newly identified CA repeat polymorphism of the estrogen receptor alpha gene (ESR1) with osteoporosis was investigated. Postmenopausal women with
ISSN:0937-941X
1433-2965
DOI:10.1007/s00198-007-0482-1