Overweight in adolescent offspring of women with hyperglycemia during pregnancy

To verify whether different hyperglycemia levels during pregnancy cause frequency differences in adolescent obesity and its morbidities in the offspring. Seventy-three children were divided into three groups according to maternal glucose tolerance: G1 (n=27) normal oral glucose tolerance test (OGTT) and daily glycemia (DG); G2 (n=23) normal OGTT and high DG; G3 (n=23) abnormal OGTT and DG (gestational diabetes mellitus; GDM). All underwent clinical evaluation (anthropometry) a questionnaire(neonatal data, eating habits), and determination of fasting serum glucose and lipid profile measurement. Analysis of variance (ANOVA) and the Goodmans test were used to compare the groups. G3 mothers showed higher fasting plasma glucose(FPG) and DG than G2 and G1(FPG: 93+/-10 vs 83+/-5 vs 78+/-10 mg/dL; DG: 104+/-12 vs 93+/-7 vs 85+/-9 mg/dL, respectively; P