Down syndrome and esophageal cancer

We present two cases of Down syndrome with inoperable esophageal cancer at a relatively young age. The first patient had a locally advanced squamous cell carcinoma of the distal esophagus. The second had a short circular adenocarcinoma of the distal esophagus with peritoneal and liver metastases. Th...

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Veröffentlicht in:	Diseases of the esophagus 2007-04, Vol.20 (2), p.183-186
Hauptverfasser:	Moreels, T. G., Van Vliet, E. P. M., Tilanus, H. W., Tran, T. C. K., Kuipers, E. J., Siersema, P. D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - complications Adenocarcinoma - diagnosis Adult Carcinoma, Squamous Cell - complications Carcinoma, Squamous Cell - diagnosis case report Deglutition Disorders - etiology Down syndrome Down Syndrome - complications Endoscopy, Digestive System esophageal cancer Esophageal Neoplasms - complications Esophageal Neoplasms - diagnosis Humans Liver Neoplasms - diagnosis Liver Neoplasms - secondary Male Peritoneal Neoplasms - diagnosis Peritoneal Neoplasms - secondary
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Beschreibung
Zusammenfassung:	We present two cases of Down syndrome with inoperable esophageal cancer at a relatively young age. The first patient had a locally advanced squamous cell carcinoma of the distal esophagus. The second had a short circular adenocarcinoma of the distal esophagus with peritoneal and liver metastases. The cases are discussed with regard to the current literature on Down syndrome and esophageal cancer.
ISSN:	1120-8694 1442-2050
DOI:	10.1111/j.1442-2050.2007.00667.x