Atovaquone-Statine "Double-Drugs" with High Antiplasmodial Activity
Combining chemicals. Malaria is one of the most widespread parasitic infections in the world, however, the unavailability of a vaccine and the spread and intensification of drug resistance over the past 15–20 years have led to a dramatic decline in the efficacy of the most affordable antimalarial dr...
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Veröffentlicht in: | ChemMedChem 2008-03, Vol.3 (3), p.418-420 |
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Hauptverfasser: | , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | Combining chemicals. Malaria is one of the most widespread parasitic infections in the world, however, the unavailability of a vaccine and the spread and intensification of drug resistance over the past 15–20 years have led to a dramatic decline in the efficacy of the most affordable antimalarial drugs. Herein, the development of “double‐drugs” to tackle inhibition of P. falciparum growth is discussed. |
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ISSN: | 1860-7179 1860-7187 |
DOI: | 10.1002/cmdc.200700166 |