One-Pot Synthesis of Substituted 2-Aminobenzo[b]thiophenes

Reaction of 1-(2-chloro-5-nitrophenyl)ethanone 1, via Willgerodt−Kindler routes, using the primary and secondary amines 2a − k resulted in a simple, efficient three-component one-pot synthesis of 2-aminobenzo[b]thiophenes 3a − k.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of organic chemistry 2007-04, Vol.72 (8), p.3122-3124
Hauptverfasser:	Solovyev, Andrey Y, Androsov, Dmitry A, Neckers, Douglas C
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry Exact sciences and technology Heterocyclic compounds Heterocyclic compounds with o, s, se, te hetero atom and condensed derivatives Organic chemistry Preparations and properties
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Beschreibung
Zusammenfassung:	Reaction of 1-(2-chloro-5-nitrophenyl)ethanone 1, via Willgerodt−Kindler routes, using the primary and secondary amines 2a − k resulted in a simple, efficient three-component one-pot synthesis of 2-aminobenzo[b]thiophenes 3a − k.
ISSN:	0022-3263 1520-6904
DOI:	10.1021/jo062141a