Copper-Catalyzed Coupling of Hydroxylamines with Aryl Iodides
An efficient method for the copper-catalyzed N-arylation of hydroxylamines with aryl iodides is described. A variety of N- and O-functionalized hydroxylamines were transformed in good to excellent yield with a broad range of aryl coupling partners. Methods for the selective deprotection of either th...
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| Veröffentlicht in: | Organic letters 2008-03, Vol.10 (5), p.797-800 |
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| container_title | Organic letters |
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| creator | Jones, Kerri L Porzelle, Achim Hall, Adrian Woodrow, Michael D Tomkinson, Nicholas C. O |
| description | An efficient method for the copper-catalyzed N-arylation of hydroxylamines with aryl iodides is described. A variety of N- and O-functionalized hydroxylamines were transformed in good to excellent yield with a broad range of aryl coupling partners. Methods for the selective deprotection of either the N- or O-substituents for further functionalization are also described. |
| doi_str_mv | 10.1021/ol7029273 |
| format | Article |
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O</creatorcontrib><title>Copper-Catalyzed Coupling of Hydroxylamines with Aryl Iodides</title><title>Organic letters</title><addtitle>Org. Lett</addtitle><description>An efficient method for the copper-catalyzed N-arylation of hydroxylamines with aryl iodides is described. A variety of N- and O-functionalized hydroxylamines were transformed in good to excellent yield with a broad range of aryl coupling partners. Methods for the selective deprotection of either the N- or O-substituents for further functionalization are also described.</description><subject>Catalysis</subject><subject>Combinatorial Chemistry Techniques</subject><subject>Copper - chemistry</subject><subject>Hydrocarbons, Iodinated - chemistry</subject><subject>Hydroxylamines - chemistry</subject><subject>Molecular Structure</subject><issn>1523-7060</issn><issn>1523-7052</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpt0EFLwzAUB_AgipvTg19AelHwUE3ymqY7eBhF3WDgRc8hTVLtSJuatLj66a1szIun93j8-MP7I3RJ8B3BlNw7yzGdUw5HaEoYhZhjRo8Pe4on6CyEDcZkvMxP0YRklOIEwxQ95K5tjY9z2Uk7fBsd5a5vbdW8R66MloP2bjtYWVeNCdFX1X1ECz_YaOV0pU04RyeltMFc7OcMvT09vubLeP3yvMoX61gCgS7WhIFO0zmAlIkyWmUspYlhRQoUKFM6kapMFSkyzTnFmclkAQnDQLgGJRnM0M0ut_XuszehE3UVlLFWNsb1QXAMo06zEd7uoPIuBG9K0fqqln4QBIvfrsShq9Fe7UP7ojb6T-7LGcH1DkgVxMb1vhl__CfoB0-4brw</recordid><startdate>20080306</startdate><enddate>20080306</enddate><creator>Jones, Kerri L</creator><creator>Porzelle, Achim</creator><creator>Hall, Adrian</creator><creator>Woodrow, Michael D</creator><creator>Tomkinson, Nicholas C. 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| identifier | ISSN: 1523-7060 |
| ispartof | Organic letters, 2008-03, Vol.10 (5), p.797-800 |
| issn | 1523-7060 1523-7052 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_70350368 |
| source | MEDLINE; American Chemical Society Journals |
| subjects | Catalysis Combinatorial Chemistry Techniques Copper - chemistry Hydrocarbons, Iodinated - chemistry Hydroxylamines - chemistry Molecular Structure |
| title | Copper-Catalyzed Coupling of Hydroxylamines with Aryl Iodides |
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