Psychiatric Manifestations in Wilson's Disease: A Cross-Sectional Analysis
Behavioral and psychiatric abnormalities in Wilson's disease (WD) have a variable frequency and spectrum. This study involved evaluation of the psychiatric comorbidities in patients of Wilson's disease, using structured clinical interview for DSM-IV Axis-I disorders (SCID). Among the 50 co...
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| Veröffentlicht in: | The journal of neuropsychiatry and clinical neurosciences 2008-01, Vol.20 (1), p.81-85 |
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| container_title | The journal of neuropsychiatry and clinical neurosciences |
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| creator | Shanmugiah, A Sinha, S Taly, A.B Prashanth, L.K Tomar, M Arunodaya, G.R Reddy, Janardhana Y.C Khanna, S |
| description | Behavioral and psychiatric abnormalities in Wilson's disease (WD) have a variable frequency and spectrum. This study involved evaluation of the psychiatric comorbidities in patients of Wilson's disease, using structured clinical interview for DSM-IV Axis-I disorders (SCID). Among the 50 confirmed patients with Wilson's disease recruited for this study, 12 patients (24%) fulfilled the diagnostic criteria for syndromic psychiatric diagnosis: bipolar affective disorder (18%), major depression (4%), and dysthymia (2%). Formal assessment of psychopathology in all patients with Wilson's disease may have therapeutic significance. |
| doi_str_mv | 10.1176/jnp.2008.20.1.81 |
| format | Article |
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This study involved evaluation of the psychiatric comorbidities in patients of Wilson's disease, using structured clinical interview for DSM-IV Axis-I disorders (SCID). Among the 50 confirmed patients with Wilson's disease recruited for this study, 12 patients (24%) fulfilled the diagnostic criteria for syndromic psychiatric diagnosis: bipolar affective disorder (18%), major depression (4%), and dysthymia (2%). Formal assessment of psychopathology in all patients with Wilson's disease may have therapeutic significance.</description><identifier>ISSN: 0895-0172</identifier><identifier>EISSN: 1545-7222</identifier><identifier>DOI: 10.1176/jnp.2008.20.1.81</identifier><identifier>PMID: 18305288</identifier><identifier>CODEN: JNCNE7</identifier><language>eng</language><publisher>Washington, DC: American Psychiatric Publishing, Inc</publisher><subject>Adolescent ; Adult ; Biological and medical sciences ; Child ; Child, Preschool ; Comorbidity ; Cross-Sectional Studies ; Diagnosis, Dual (Psychiatry) ; Diagnostic and Statistical Manual of Mental Disorders ; Female ; Hepatolenticular Degeneration - epidemiology ; Humans ; Interview, Psychological ; Magnetic Resonance Imaging - methods ; Male ; Medical sciences ; Mental Disorders - epidemiology ; Metabolic diseases ; Metals (hemochromatosis...) ; Other metabolic disorders ; Psychiatric Status Rating Scales</subject><ispartof>The journal of neuropsychiatry and clinical neurosciences, 2008-01, Vol.20 (1), p.81-85</ispartof><rights>2008 INIST-CNRS</rights><rights>Copyright American Psychiatric Publishing, Inc. 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Sinha, S ; Taly, A.B ; Prashanth, L.K ; Tomar, M ; Arunodaya, G.R ; Reddy, Janardhana Y.C ; Khanna, S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a307t-8808f564159cf2af9eae1263f7f68ef91e3411007583a77facc26f04e5eff14d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Comorbidity</topic><topic>Cross-Sectional Studies</topic><topic>Diagnosis, Dual (Psychiatry)</topic><topic>Diagnostic and Statistical Manual of Mental Disorders</topic><topic>Female</topic><topic>Hepatolenticular Degeneration - epidemiology</topic><topic>Humans</topic><topic>Interview, Psychological</topic><topic>Magnetic Resonance Imaging - methods</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Mental Disorders - epidemiology</topic><topic>Metabolic diseases</topic><topic>Metals (hemochromatosis...)</topic><topic>Other metabolic disorders</topic><topic>Psychiatric Status Rating Scales</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shanmugiah, A</creatorcontrib><creatorcontrib>Sinha, S</creatorcontrib><creatorcontrib>Taly, A.B</creatorcontrib><creatorcontrib>Prashanth, L.K</creatorcontrib><creatorcontrib>Tomar, M</creatorcontrib><creatorcontrib>Arunodaya, G.R</creatorcontrib><creatorcontrib>Reddy, Janardhana Y.C</creatorcontrib><creatorcontrib>Khanna, S</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>The journal of neuropsychiatry and clinical neurosciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shanmugiah, A</au><au>Sinha, S</au><au>Taly, A.B</au><au>Prashanth, L.K</au><au>Tomar, M</au><au>Arunodaya, G.R</au><au>Reddy, Janardhana Y.C</au><au>Khanna, S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Psychiatric Manifestations in Wilson's Disease: A Cross-Sectional Analysis</atitle><jtitle>The journal of neuropsychiatry and clinical neurosciences</jtitle><addtitle>J Neuropsychiatry Clin Neurosci</addtitle><date>2008-01</date><risdate>2008</risdate><volume>20</volume><issue>1</issue><spage>81</spage><epage>85</epage><pages>81-85</pages><issn>0895-0172</issn><eissn>1545-7222</eissn><coden>JNCNE7</coden><abstract>Behavioral and psychiatric abnormalities in Wilson's disease (WD) have a variable frequency and spectrum. 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| source | MEDLINE; American Psychiatric Publishing Journals (1997-Present); Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Adolescent Adult Biological and medical sciences Child Child, Preschool Comorbidity Cross-Sectional Studies Diagnosis, Dual (Psychiatry) Diagnostic and Statistical Manual of Mental Disorders Female Hepatolenticular Degeneration - epidemiology Humans Interview, Psychological Magnetic Resonance Imaging - methods Male Medical sciences Mental Disorders - epidemiology Metabolic diseases Metals (hemochromatosis...) Other metabolic disorders Psychiatric Status Rating Scales |
| title | Psychiatric Manifestations in Wilson's Disease: A Cross-Sectional Analysis |
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