Psychiatric Manifestations in Wilson's Disease: A Cross-Sectional Analysis

Behavioral and psychiatric abnormalities in Wilson's disease (WD) have a variable frequency and spectrum. This study involved evaluation of the psychiatric comorbidities in patients of Wilson's disease, using structured clinical interview for DSM-IV Axis-I disorders (SCID). Among the 50 co...

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Veröffentlicht in:	The journal of neuropsychiatry and clinical neurosciences 2008-01, Vol.20 (1), p.81-85
Hauptverfasser:	Shanmugiah, A, Sinha, S, Taly, A.B, Prashanth, L.K, Tomar, M, Arunodaya, G.R, Reddy, Janardhana Y.C, Khanna, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Biological and medical sciences Child Child, Preschool Comorbidity Cross-Sectional Studies Diagnosis, Dual (Psychiatry) Diagnostic and Statistical Manual of Mental Disorders Female Hepatolenticular Degeneration - epidemiology Humans Interview, Psychological Magnetic Resonance Imaging - methods Male Medical sciences Mental Disorders - epidemiology Metabolic diseases Metals (hemochromatosis...) Other metabolic disorders Psychiatric Status Rating Scales
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Beschreibung
Zusammenfassung:	Behavioral and psychiatric abnormalities in Wilson's disease (WD) have a variable frequency and spectrum. This study involved evaluation of the psychiatric comorbidities in patients of Wilson's disease, using structured clinical interview for DSM-IV Axis-I disorders (SCID). Among the 50 confirmed patients with Wilson's disease recruited for this study, 12 patients (24%) fulfilled the diagnostic criteria for syndromic psychiatric diagnosis: bipolar affective disorder (18%), major depression (4%), and dysthymia (2%). Formal assessment of psychopathology in all patients with Wilson's disease may have therapeutic significance.
ISSN:	0895-0172 1545-7222
DOI:	10.1176/jnp.2008.20.1.81