Localized biosensing with Topas microstructured polymer optical fiber

We present what is believed to be the first microstructured polymer optical fiber (mPOF) fabricated from Topas cyclic olefin copolymer, which has attractive material and biochemical properties. This polymer allows for a novel type of fiber-optic biosensor, where localized sensor layers may be activa...

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Veröffentlicht in:	Optics letters 2007-03, Vol.32 (5), p.460-462
Hauptverfasser:	EMILIYANOV, Grigoriy, JENSEN, Jesper B, BANG, Ole, HOIBY, Poul E, PEDERSEN, Lars H, KJAER, Erik M, LINDVOLD, Lars
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkenes - chemistry Applied sciences Biocompatible Materials - chemistry Biological and medical sciences Biosensing Techniques Biosensors Biotechnology C-Reactive Protein - chemistry Carbocyanines - chemistry Circuit properties Electric, optical and optoelectronic circuits Electronics Exact sciences and technology Fiber Optic Technology Fundamental and applied biological sciences. Psychology General equipment and techniques Instruments, apparatus, components and techniques common to several branches of physics and astronomy Integrated optics. Optical fibers and wave guides Methods. Procedures. Technologies Microscopy, Fluorescence - instrumentation Microscopy, Fluorescence - methods Optical and optoelectronic circuits Optical Fibers Optics and Photonics Physics Polymers - chemistry Polymethyl Methacrylate - chemistry Sensors (chemical, optical, electrical, movement, gas, etc.) remote sensing Streptavidin - chemistry Ultraviolet Rays Various methods and equipments
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Beschreibung
Zusammenfassung:	We present what is believed to be the first microstructured polymer optical fiber (mPOF) fabricated from Topas cyclic olefin copolymer, which has attractive material and biochemical properties. This polymer allows for a novel type of fiber-optic biosensor, where localized sensor layers may be activated on the inner side of the air holes in a predetermined section of the mPOF. The concept is demonstrated using a fluorescence-based method for selective detection of fluorophore-labeled antibodies.
ISSN:	0146-9592 1539-4794
DOI:	10.1364/OL.32.000460