Improving Hand Function in Stroke Survivors: A Pilot Study of Contralaterally Controlled Functional Electric Stimulation in Chronic Hemiplegia

Abstract Knutson JS, Harley MY, Hisel TZ, Chae J. Improving hand function in stroke survivors: a pilot study of contralaterally controlled functional electric stimulation in chronic hemiplegia. Objective To assess the feasibility of a new stroke rehabilitation therapy for the hemiparetic hand. Design Case series. Pre- and postintervention assessment with 1- and 3-month follow-ups. Setting Clinical research laboratory of a large public hospital. Participants Three subjects with chronic (>6mo postcerebrovascular accident) upper-extremity hemiplegia. Intervention Subjects used an electric stimulator to cause the paretic hand extensor muscles to contract and thereby open the hand. Subjects controlled the intensity of the stimulation, and thus the degree of hand opening, by volitionally opening the unimpaired contralateral hand, which was detected by an instrumented glove. For 6 weeks, subjects used the stimulator to perform active repetitive hand-opening exercises 2 hours daily at home and functional tasks 1.5 hours twice a week in the laboratory. Main Outcome Measures Maximum voluntary finger extension, maximum voluntary isometric finger-extension moment, finger-movement control, and box and block test (BBT) score at pre- and posttreatment and at 1 month and 3 months posttreatment. Results Maximum voluntary finger extension increased from baseline to end of treatment and from the end of treatment to 1-month follow-up in 2 subjects. Maximum voluntary isometric finger-extension moment, finger-movement control, and BBT score increased from baseline to the end of treatment and from the end of treatment to 1-month follow-up in all 3 subjects. The improvements generally declined at 3 months. Conclusions The results suggest a positive effect on motor impairment, meriting further investigation of the intervention.