Total Synthesis of Phalarine

Total Synthesis of Phalarine

End of the expedition …︁ for now: Completion of the first total synthesis of phalarine from an advanced rearrangement product brought up interesting obstacles to overcome. Use of the Gassman oxindole synthesis and subsequent manipulations led to the racemic natural product (see scheme, Ts=toluene‐4‐...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Angewandte Chemie International Edition 2007-01, Vol.46 (9), p.1448-1450
Hauptverfasser: Li, Chaomin, Chan, Collin, Heimann, Annekatrin C., Danishefsky, Samuel J.
Format: Artikel
Sprache:eng
Schlagworte:
alkaloids
Alkaloids - chemical synthesis
Alkaloids - chemistry
Aza Compounds - chemistry
Furans - chemical synthesis
Furans - chemistry
heterocycles
indoles
Indoles - chemistry
Models, Chemical
Molecular Structure
oxindoles
Stereoisomerism
total synthesis
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:End of the expedition …︁ for now: Completion of the first total synthesis of phalarine from an advanced rearrangement product brought up interesting obstacles to overcome. Use of the Gassman oxindole synthesis and subsequent manipulations led to the racemic natural product (see scheme, Ts=toluene‐4‐sulfonyl).
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200604072