Clinical and Biochemical Assessment of Hypogonadism in Men With Type 2 Diabetes: Correlations with bioavailable testosterone and visceral adiposity

OBJECTIVE:--The aim of our study was to assess the prevalence of clinical hypogonadism, based on both symptoms and biochemical available measures of testosterone deficiency, in men with type 2 diabetes. RESEARCH DESIGN AND METHODS--In a cross-sectional study of 355 type 2 diabetic men aged >30 ye...

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Veröffentlicht in:	Diabetes care 2007-04, Vol.30 (4), p.911-917
Hauptverfasser:	Kapoor, Dheeraj, Aldred, Hazel, Clark, Stephanie, Channer, Kevin S, Jones, T. Hugh
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue - anatomy & histology Adult Aged Aged, 80 and over Aging Androgens Biological and medical sciences Biological Availability Body Mass Index Body Size Clinical trials Cross-Sectional Studies Diabetes Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - epidemiology Diabetes Mellitus, Type 2 - physiopathology Diabetes. Impaired glucose tolerance Diagnosis Drug therapy Endocrine pancreas. Apud cells (diseases) Endocrinology Endocrinopathies Erectile Dysfunction - blood Erectile Dysfunction - epidemiology Erectile Dysfunction - physiopathology Etiopathogenesis. Screening. Investigations. Target tissue resistance Health aspects Hormone replacement therapy Humans Hypogonadism Hypogonadism - blood Hypogonadism - epidemiology Hypogonadism - physiopathology Male Medical sciences Men Middle Aged Obesity - epidemiology Sex Hormone-Binding Globulin - analysis Testosterone Testosterone - blood Type 2 diabetes Viscera
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Zusammenfassung:	OBJECTIVE:--The aim of our study was to assess the prevalence of clinical hypogonadism, based on both symptoms and biochemical available measures of testosterone deficiency, in men with type 2 diabetes. RESEARCH DESIGN AND METHODS--In a cross-sectional study of 355 type 2 diabetic men aged >30 years, total and bioavailable testosterone, sex hormone-binding globulin, BMI, and waist circumference were measured and free testosterone was calculated. Overt hypogonadism was defined as the presence of clinical symptoms of hypogonadism and low testosterone level (total testosterone
ISSN:	0149-5992 1935-5548
DOI:	10.2337/dc06-1426