Ovarian Transplantation in a Series of Monozygotic Twins Discordant for Ovarian Failure

To the Editor: We previously reported in the Journal a case of a successful ovarian transplantation between 25-year-old monozygotic twins. One had undergone menopause at the age of 14 years, whereas the other was still fertile. 1 After receiving a graft of ovarian tissue from her sibling, the previously menopausal twin conceived spontaneously during the second menstrual cycle and delivered a healthy full-term baby. Subsequently, 10 other pairs of monozygotic twins who were discordant for ovarian failure sought consultation at our center for ovarian transplantation. Four women had previously failed to conceive after receiving donor eggs through in vitro fertilization (IVF), . . .