Fructose Intolerance in IBS and Utility of Fructose-Restricted Diet
INTRODUCTIONWhether dietary fructose intolerance causes symptoms of irritable bowel syndrome (IBS) is unclear. We examined the prevalence of fructose intolerance in IBS and long-term outcome of fructose-restricted diet. METHODSTwo hundred and nine patients with suspected IBS were retrospectively eva...
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Veröffentlicht in: | Journal of clinical gastroenterology 2008-03, Vol.42 (3), p.233-238 |
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Zusammenfassung: | INTRODUCTIONWhether dietary fructose intolerance causes symptoms of irritable bowel syndrome (IBS) is unclear. We examined the prevalence of fructose intolerance in IBS and long-term outcome of fructose-restricted diet.
METHODSTwo hundred and nine patients with suspected IBS were retrospectively evaluated for organic illnesses. Patients with IBS (Rome II) and positive fructose breath test received instructions regarding fructose-restricted diet. One year later, their symptoms, compliance with, and effects of dietary modification on lifestyle were assessed using a structured interview.
RESULTSEighty patients (m/f=26/54) fulfilled Rome II criteria. Of 80 patients, 31 (38%) had positive breath test. Of 31 patients, 26 (84%) participated in follow-up (mean=13 mo) evaluation. Of 26 patients, 14 (53%) were compliant with diet; mean compliance=71%. In this group, pain, belching, bloating, fullness, indigestion, and diarrhea improved (P0.05).
CONCLUSIONSAbout one-third of patients with suspected IBS had fructose intolerance. When compliant, symptoms improved on fructose-restricted diet despite moderate impact on lifestyle; noncompliance was associated with persistent symptoms. Fructose intolerance is another jigsaw piece of the IBS puzzle that may respond to dietary modification. |
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ISSN: | 0192-0790 1539-2031 |
DOI: | 10.1097/MCG.0b013e31802cbc2f |