Reactivity Study of 1H-Thieno[3,2-d][1,3]oxazine-2,4-dione toward the Synthesis of Bicyclic 3,4-Dihydro-1H-thieno[3,2-e][1,4]diazepine-2,5-dione Analogues
A series of 10 optically pure 3,4-dihydro-1H-thieno[3,2-e][1,4]diazepine-2,5-dione derivatives has been synthesized in 41−75% yields on treatment of 1H-thieno[3,2-d][1,3]oxazine-2,4-dione with different natural α-amino acids.
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Veröffentlicht in: | Journal of organic chemistry 2007-03, Vol.72 (7), p.2662-2665 |
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container_title | Journal of organic chemistry |
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creator | Brouillette, Yann Lisowski, Vincent Fulcrand, Pierre Martinez, Jean |
description | A series of 10 optically pure 3,4-dihydro-1H-thieno[3,2-e][1,4]diazepine-2,5-dione derivatives has been synthesized in 41−75% yields on treatment of 1H-thieno[3,2-d][1,3]oxazine-2,4-dione with different natural α-amino acids. |
doi_str_mv | 10.1021/jo0622882 |
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source | MEDLINE; American Chemical Society Journals |
subjects | Amides - chemistry Anhydrides - chemistry Azepines - chemical synthesis Azepines - chemistry Chemistry Exact sciences and technology Heterocyclic compounds Heterocyclic compounds with n hetero atom and also o and/or s, se, te hetero atoms Molecular Structure Organic chemistry Oxazines - chemical synthesis Oxazines - chemistry Preparations and properties |
title | Reactivity Study of 1H-Thieno[3,2-d][1,3]oxazine-2,4-dione toward the Synthesis of Bicyclic 3,4-Dihydro-1H-thieno[3,2-e][1,4]diazepine-2,5-dione Analogues |
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