Reactivity Study of 1H-Thieno[3,2-d][1,3]oxazine-2,4-dione toward the Synthesis of Bicyclic 3,4-Dihydro-1H-thieno[3,2-e][1,4]diazepine-2,5-dione Analogues

Reactivity Study of 1H-Thieno[3,2-d][1,3]oxazine-2,4-dione toward the Synthesis of Bicyclic 3,4-Dihydro-1H-thieno[3,2-e][1,4]diazepine-2,5-dione Analogues

A series of 10 optically pure 3,4-dihydro-1H-thieno[3,2-e][1,4]diazepine-2,5-dione derivatives has been synthesized in 41−75% yields on treatment of 1H-thieno[3,2-d][1,3]oxazine-2,4-dione with different natural α-amino acids.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of organic chemistry 2007-03, Vol.72 (7), p.2662-2665
Hauptverfasser: Brouillette, Yann, Lisowski, Vincent, Fulcrand, Pierre, Martinez, Jean
Format: Artikel
Sprache:eng
Schlagworte:
Amides - chemistry
Anhydrides - chemistry
Azepines - chemical synthesis
Azepines - chemistry
Chemistry
Exact sciences and technology
Heterocyclic compounds
Heterocyclic compounds with n hetero atom and also o and/or s, se, te hetero atoms
Molecular Structure
Organic chemistry
Oxazines - chemical synthesis
Oxazines - chemistry
Preparations and properties
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A series of 10 optically pure 3,4-dihydro-1H-thieno[3,2-e][1,4]diazepine-2,5-dione derivatives has been synthesized in 41−75% yields on treatment of 1H-thieno[3,2-d][1,3]oxazine-2,4-dione with different natural α-amino acids.
ISSN:0022-3263
1520-6904
DOI:10.1021/jo0622882