Abortions in dromedaries (Camelus dromedarius) caused by equine rhinitis A virus

1 Central Veterinary Research Laboratory, PO Box 597, Dubai, United Arab Emirates 2 Institute for Animal Health (IAH), Pirbright Laboratory, Ash Road, Pirbright, Woking, Surrey GU24 0NF, UK Correspondence Nick J. Knowles nick.knowles{at}bbsrc.ac.uk A virus was isolated from aborted dromedary ( Camel...

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Veröffentlicht in:Journal of general virology 2008-03, Vol.89 (3), p.660-666
Hauptverfasser: Wernery, Ulrich, Knowles, Nick J, Hamblin, Chris, Wernery, Renate, Joseph, Sunitha, Kinne, Joerg, Nagy, Peter
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Sprache:eng
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Zusammenfassung:1 Central Veterinary Research Laboratory, PO Box 597, Dubai, United Arab Emirates 2 Institute for Animal Health (IAH), Pirbright Laboratory, Ash Road, Pirbright, Woking, Surrey GU24 0NF, UK Correspondence Nick J. Knowles nick.knowles{at}bbsrc.ac.uk A virus was isolated from aborted dromedary ( Camelus dromedarius ) fetuses during an abortion storm in Dubai, United Arab Emirates. Laboratory investigations showed the causative agent to be indistinguishable from equine rhinitis A virus (ERAV), a picornavirus. Two pregnant dromedaries experimentally infected with the camel virus isolate both aborted and an identical virus was reisolated from both fetuses, thus confirming the diagnosis. The extremely high prevalence of antibody (>90 %) and the high titres recorded against ERAV in the dromedary herd clearly showed that ERAV does infect dromedaries. Unlike horses, where ERAV targets the upper respiratory tract, in dromedaries the target organ appears to be the genital tract. The GenBank/EMBL/DDBJ accession numbers for the sequences determined in this paper are EF204767–EF204772.
ISSN:0022-1317
1465-2099
DOI:10.1099/vir.0.82215-0