STIM1 Is a MT-Plus-End-Tracking Protein Involved in Remodeling of the ER

Stromal interaction molecule 1 (STIM1) is a transmembrane protein that is essential for store-operated Ca2+ entry, a process of extracellular Ca2+ influx in response to the depletion of Ca2+ stores in the endoplasmic reticulum (ER) (reviewed in [1–4]). STIM1 localizes predominantly to the ER; upon C...

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Veröffentlicht in:	Current biology 2008-02, Vol.18 (3), p.177-182
Hauptverfasser:	Grigoriev, Ilya, Gouveia, Susana Montenegro, van der Vaart, Babet, Demmers, Jeroen, Smyth, Jeremy T., Honnappa, Srinivas, Splinter, Daniël, Steinmetz, Michel O., Putney, James W., Hoogenraad, Casper C., Akhmanova, Anna
Format:	Artikel
Sprache:	eng
Schlagworte:	Calcium - metabolism CELLBIO Endoplasmic Reticulum - metabolism Gene Expression Regulation HeLa Cells Humans Membrane Proteins - genetics Membrane Proteins - metabolism Microtubule-Associated Proteins - metabolism Microtubules - metabolism Neoplasm Proteins - genetics Neoplasm Proteins - metabolism SIGNALING Stromal Interaction Molecule 1
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