Proton pump-inhibiting drugs, calcium homeostasis, and bone health

Proton pump inhibitors (PPIs) are commonly used drugs, several of which are available without a prescription. Two recent studies have demonstrated increased hip fracture rates associated with PPI use. Theoretically, PPIs could impair intestinal calcium absorption resulting in increased rates of bone...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nutrition reviews 2008-02, Vol.66 (2), p.103-108
Hauptverfasser:	Wright, M.J, Proctor, D.D, Insogna, K.L, Kerstetter, J.E
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Bone and Bones - drug effects Bone and Bones - metabolism bone density Bone Density - drug effects bone fractures Bone Resorption calcium Calcium - metabolism calcium absorption drug therapy Fractures Fractures, Bone - chemically induced Fractures, Bone - epidemiology gastric acid Gastroenterology. Liver. Pancreas. Abdomen health status Hip Fractures - chemically induced Hip Fractures - epidemiology Homeostasis Humans Inhibitor drugs intestinal absorption literature reviews Medical sciences mineral metabolism osteoporosis Other diseases. Semiology proton pump proton pump inhibitors Proton Pump Inhibitors - adverse effects Proton Pump Inhibitors - therapeutic use Risk factors Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Studies
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Proton pump inhibitors (PPIs) are commonly used drugs, several of which are available without a prescription. Two recent studies have demonstrated increased hip fracture rates associated with PPI use. Theoretically, PPIs could impair intestinal calcium absorption resulting in increased rates of bone loss and a greater risk of fragility fracture.
ISSN:	0029-6643 1753-4887
DOI:	10.1111/j.1753-4887.2008.00015.x