Neurological morbidity and the pertussis vaccine: An old story revisited

We describe 3 children with neurological disorders that developed in association with their receipt of the whole-cell pertussis vaccine. Newer studies supported the ability of the wP vaccine to adversely affect the CNS. The possibility that it worsened their clinical course in infancy by causing add...

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Veröffentlicht in:	Scandinavian journal of infectious diseases 2007, Vol.39 (1), p.83-86
Hauptverfasser:	Schupper, Aviv, Shuper, Avinoam
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Bacterial diseases Biological and medical sciences Child Diphtheria-Tetanus-Pertussis Vaccine - adverse effects Ent and stomatologic bacterial diseases Epilepsy - complications Epilepsy - immunology Female Human bacterial diseases Humans Immunization Schedule Immunization, Secondary - adverse effects Infectious diseases Male Medical sciences Neurodegenerative Diseases - complications Neurodegenerative Diseases - immunology Pertussis Vaccine - adverse effects
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Beschreibung
Zusammenfassung:	We describe 3 children with neurological disorders that developed in association with their receipt of the whole-cell pertussis vaccine. Newer studies supported the ability of the wP vaccine to adversely affect the CNS. The possibility that it worsened their clinical course in infancy by causing additional damage should not be disregarded.
ISSN:	0036-5548 1651-1980
DOI:	10.1080/00365540600786556