Loop dynamics in DNA denaturation

The dynamics of a loop in DNA molecules at the denaturation transition is studied by scaling arguments and numerical simulations. The autocorrelation function of the state of complementary bases (either closed or open) is calculated. The long-time decay of the autocorrelation function is expressed i...

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Veröffentlicht in:Physical review letters 2007-01, Vol.98 (3), p.038103-038103, Article 038103
Hauptverfasser: Bar, A, Kafri, Y, Mukamel, D
Format: Artikel
Sprache:eng
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Zusammenfassung:The dynamics of a loop in DNA molecules at the denaturation transition is studied by scaling arguments and numerical simulations. The autocorrelation function of the state of complementary bases (either closed or open) is calculated. The long-time decay of the autocorrelation function is expressed in terms of the loop exponent c both for homopolymers and heteropolymers. This suggests an experimental method for measuring the exponent c using florescence correlation spectroscopy.
ISSN:0031-9007
1079-7114
DOI:10.1103/PhysRevLett.98.038103