High-resolution frequency-domain second-harmonic optical coherence tomography

We used continuum generated in an 8.5 cm long fiber by a femtosecond Yb fiber laser to improve threefold the axial resolution of frequency domain second-harmonic optical coherence tomography (SH-OCT) to 12 microm. The acquisition time was shortened by more than 2 orders of magnitude compared to the...

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Veröffentlicht in:	Applied Optics 2007-04, Vol.46 (10), p.1770-1775
Hauptverfasser:	Su, Jianping, Tomov, Ivan V, Jiang, Yi, Chen, Zhongping
Format:	Artikel
Sprache:	eng
Schlagworte:	Equipment Design Equipment Failure Analysis Image Enhancement - instrumentation Image Enhancement - methods Image Interpretation, Computer-Assisted - instrumentation Image Interpretation, Computer-Assisted - methods Reproducibility of Results Sensitivity and Specificity Tomography, Optical Coherence - instrumentation Tomography, Optical Coherence - methods
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Zusammenfassung:	We used continuum generated in an 8.5 cm long fiber by a femtosecond Yb fiber laser to improve threefold the axial resolution of frequency domain second-harmonic optical coherence tomography (SH-OCT) to 12 microm. The acquisition time was shortened by more than 2 orders of magnitude compared to the time-domain SH-OCT. The system was applied to image biological tissue of fish scales, pig leg tendon, and rabbit eye sclera. Highly organized collagen fibrils can be visualized in the recorded images. Polarization dependence on the SH has been used to obtain polarization resolved images.
ISSN:	1559-128X 0003-6935 1539-4522
DOI:	10.1364/AO.46.001770