Treatment of Restenosis with a Paclitaxel-Coated Balloon Catheter

To the Editor: We question the conclusion by Scheller and colleagues (Nov. 16 issue) 1 that paclitaxel-coated balloon catheters significantly reduce the incidence of adverse outcomes in patients undergoing percutaneous coronary intervention for in-stent stenosis. First, the trial was reported to be...

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Veröffentlicht in:The New England journal of medicine 2007-03, Vol.356 (10), p.1071-1073
Hauptverfasser: Sun, Jack C.J, Eikelboom, John W, Agostoni, Pierfrancesco, Sangiorgi, Giuseppe M, Biondi-Zoccai, Giuseppe G, Scheller, Bruno, Böhm, Michael, Camenzind, Edoardo
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Sprache:eng
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Zusammenfassung:To the Editor: We question the conclusion by Scheller and colleagues (Nov. 16 issue) 1 that paclitaxel-coated balloon catheters significantly reduce the incidence of adverse outcomes in patients undergoing percutaneous coronary intervention for in-stent stenosis. First, the trial was reported to be a double-blind study, but the investigators were aware of assignments to study groups because the paclitaxel-coated balloons were a different color from the uncoated balloons. The reduction in major cardiac events in patients who received treatment with a paclitaxel-coated balloon was driven primarily by a reduction in target-lesion revascularization, a subjective end point that was based on symptoms and . . .
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMc063527