Long QT Syndrome and Pregnancy
Long QT Syndrome and Pregnancy Rahul Seth, Arthur J. Moss, Scott McNitt, Wojciech Zareba, Mark L. Andrews, Ming Qi, Jennifer L. Robinson, Ilan Goldenberg, Michael J. Ackerman, Jesaia Benhorin, Elizabeth S. Kaufman, Emanuela H. Locati, Carlo Napolitano, Silvia G. Priori, Peter J. Schwartz, Jeffrey A....
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Veröffentlicht in: | Journal of the American College of Cardiology 2007-03, Vol.49 (10), p.1092-1098 |
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creator | Seth, Rahul, MD Moss, Arthur J., MD McNitt, Scott, MS Zareba, Wojciech, MD, PhD Andrews, Mark L., BBA Qi, Ming, PhD Robinson, Jennifer L., MS Goldenberg, Ilan, MD Ackerman, Michael J., MD, PhD Benhorin, Jesaia, MD Kaufman, Elizabeth S., MD Locati, Emanuela H., MD, PhD Napolitano, Carlo, MD Priori, Silvia G., MD, PhD Schwartz, Peter J., MD Towbin, Jeffrey A., MD Vincent, G. Michael, MD Zhang, Li, MD |
description | Long QT Syndrome and Pregnancy Rahul Seth, Arthur J. Moss, Scott McNitt, Wojciech Zareba, Mark L. Andrews, Ming Qi, Jennifer L. Robinson, Ilan Goldenberg, Michael J. Ackerman, Jesaia Benhorin, Elizabeth S. Kaufman, Emanuela H. Locati, Carlo Napolitano, Silvia G. Priori, Peter J. Schwartz, Jeffrey A. Towbin, G. Michael Vincent, Li Zhang The risk of experiencing an adverse cardiac event, including syncope, aborted cardiac arrest, and sudden death, during and after pregnancy was analyzed for women who had their first birth from 1980 to 2003 (n = 391). Compared with a time period before a woman’s first conception, the pregnancy time was associated with a reduced risk of cardiac events and an increased risk during the 9-month postpartum period, especially among women with the LQT2 genotype. Beta-blockers were associated with a reduction in cardiac events during the high-risk postpartum time period. |
doi_str_mv | 10.1016/j.jacc.2006.09.054 |
format | Article |
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Michael, MD ; Zhang, Li, MD</creator><creatorcontrib>Seth, Rahul, MD ; Moss, Arthur J., MD ; McNitt, Scott, MS ; Zareba, Wojciech, MD, PhD ; Andrews, Mark L., BBA ; Qi, Ming, PhD ; Robinson, Jennifer L., MS ; Goldenberg, Ilan, MD ; Ackerman, Michael J., MD, PhD ; Benhorin, Jesaia, MD ; Kaufman, Elizabeth S., MD ; Locati, Emanuela H., MD, PhD ; Napolitano, Carlo, MD ; Priori, Silvia G., MD, PhD ; Schwartz, Peter J., MD ; Towbin, Jeffrey A., MD ; Vincent, G. Michael, MD ; Zhang, Li, MD</creatorcontrib><description>Long QT Syndrome and Pregnancy Rahul Seth, Arthur J. Moss, Scott McNitt, Wojciech Zareba, Mark L. Andrews, Ming Qi, Jennifer L. Robinson, Ilan Goldenberg, Michael J. Ackerman, Jesaia Benhorin, Elizabeth S. Kaufman, Emanuela H. Locati, Carlo Napolitano, Silvia G. Priori, Peter J. Schwartz, Jeffrey A. Towbin, G. Michael Vincent, Li Zhang The risk of experiencing an adverse cardiac event, including syncope, aborted cardiac arrest, and sudden death, during and after pregnancy was analyzed for women who had their first birth from 1980 to 2003 (n = 391). Compared with a time period before a woman’s first conception, the pregnancy time was associated with a reduced risk of cardiac events and an increased risk during the 9-month postpartum period, especially among women with the LQT2 genotype. Beta-blockers were associated with a reduction in cardiac events during the high-risk postpartum time period.</description><identifier>ISSN: 0735-1097</identifier><identifier>EISSN: 1558-3597</identifier><identifier>DOI: 10.1016/j.jacc.2006.09.054</identifier><identifier>PMID: 17349890</identifier><identifier>CODEN: JACCDI</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Abortion ; Adult ; Age ; Biological and medical sciences ; Births ; Cardiac dysrhythmias ; Cardiology ; Cardiology. Vascular system ; Cardiovascular ; Cohort Studies ; Confidence Intervals ; Death, Sudden, Cardiac - epidemiology ; Death, Sudden, Cardiac - etiology ; Drug therapy ; Electrocardiography ; Female ; Follow-Up Studies ; Genotype & phenotype ; Gestational Age ; Heart ; Heart Arrest - mortality ; Heart attacks ; Heart rate ; Humans ; Internal Medicine ; Long QT syndrome ; Long QT Syndrome - diagnosis ; Long QT Syndrome - mortality ; Medical sciences ; Mutation ; Older people ; Parity ; Population ; Postpartum Period ; Pregnancy ; Pregnancy Complications, Cardiovascular - diagnosis ; Pregnancy Complications, Cardiovascular - mortality ; Pregnancy Outcome ; Pregnancy, High-Risk ; Probability ; Proportional Hazards Models ; Ratios ; Registries ; Retrospective Studies ; Risk Assessment ; Studies ; Womens health</subject><ispartof>Journal of the American College of Cardiology, 2007-03, Vol.49 (10), p.1092-1098</ispartof><rights>American College of Cardiology Foundation</rights><rights>2007 American College of Cardiology Foundation</rights><rights>2007 INIST-CNRS</rights><rights>Copyright Elsevier Limited Mar 13, 2007</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c547t-b70bcd9c879294ab92354133a11ce87f5e40de7206d76758dc5eb31eeefe9fbd3</citedby><cites>FETCH-LOGICAL-c547t-b70bcd9c879294ab92354133a11ce87f5e40de7206d76758dc5eb31eeefe9fbd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jacc.2006.09.054$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,3548,27922,27923,45993</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=18588009$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17349890$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Seth, Rahul, MD</creatorcontrib><creatorcontrib>Moss, Arthur J., MD</creatorcontrib><creatorcontrib>McNitt, Scott, MS</creatorcontrib><creatorcontrib>Zareba, Wojciech, MD, PhD</creatorcontrib><creatorcontrib>Andrews, Mark L., BBA</creatorcontrib><creatorcontrib>Qi, Ming, PhD</creatorcontrib><creatorcontrib>Robinson, Jennifer L., MS</creatorcontrib><creatorcontrib>Goldenberg, Ilan, MD</creatorcontrib><creatorcontrib>Ackerman, Michael J., MD, PhD</creatorcontrib><creatorcontrib>Benhorin, Jesaia, MD</creatorcontrib><creatorcontrib>Kaufman, Elizabeth S., MD</creatorcontrib><creatorcontrib>Locati, Emanuela H., MD, PhD</creatorcontrib><creatorcontrib>Napolitano, Carlo, MD</creatorcontrib><creatorcontrib>Priori, Silvia G., MD, PhD</creatorcontrib><creatorcontrib>Schwartz, Peter J., MD</creatorcontrib><creatorcontrib>Towbin, Jeffrey A., MD</creatorcontrib><creatorcontrib>Vincent, G. Michael, MD</creatorcontrib><creatorcontrib>Zhang, Li, MD</creatorcontrib><title>Long QT Syndrome and Pregnancy</title><title>Journal of the American College of Cardiology</title><addtitle>J Am Coll Cardiol</addtitle><description>Long QT Syndrome and Pregnancy Rahul Seth, Arthur J. Moss, Scott McNitt, Wojciech Zareba, Mark L. Andrews, Ming Qi, Jennifer L. Robinson, Ilan Goldenberg, Michael J. Ackerman, Jesaia Benhorin, Elizabeth S. Kaufman, Emanuela H. Locati, Carlo Napolitano, Silvia G. Priori, Peter J. Schwartz, Jeffrey A. Towbin, G. Michael Vincent, Li Zhang The risk of experiencing an adverse cardiac event, including syncope, aborted cardiac arrest, and sudden death, during and after pregnancy was analyzed for women who had their first birth from 1980 to 2003 (n = 391). Compared with a time period before a woman’s first conception, the pregnancy time was associated with a reduced risk of cardiac events and an increased risk during the 9-month postpartum period, especially among women with the LQT2 genotype. Beta-blockers were associated with a reduction in cardiac events during the high-risk postpartum time period.</description><subject>Abortion</subject><subject>Adult</subject><subject>Age</subject><subject>Biological and medical sciences</subject><subject>Births</subject><subject>Cardiac dysrhythmias</subject><subject>Cardiology</subject><subject>Cardiology. Vascular system</subject><subject>Cardiovascular</subject><subject>Cohort Studies</subject><subject>Confidence Intervals</subject><subject>Death, Sudden, Cardiac - epidemiology</subject><subject>Death, Sudden, Cardiac - etiology</subject><subject>Drug therapy</subject><subject>Electrocardiography</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Genotype & phenotype</subject><subject>Gestational Age</subject><subject>Heart</subject><subject>Heart Arrest - mortality</subject><subject>Heart attacks</subject><subject>Heart rate</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Long QT syndrome</subject><subject>Long QT Syndrome - diagnosis</subject><subject>Long QT Syndrome - mortality</subject><subject>Medical sciences</subject><subject>Mutation</subject><subject>Older people</subject><subject>Parity</subject><subject>Population</subject><subject>Postpartum Period</subject><subject>Pregnancy</subject><subject>Pregnancy Complications, Cardiovascular - diagnosis</subject><subject>Pregnancy Complications, Cardiovascular - mortality</subject><subject>Pregnancy Outcome</subject><subject>Pregnancy, High-Risk</subject><subject>Probability</subject><subject>Proportional Hazards Models</subject><subject>Ratios</subject><subject>Registries</subject><subject>Retrospective Studies</subject><subject>Risk Assessment</subject><subject>Studies</subject><subject>Womens health</subject><issn>0735-1097</issn><issn>1558-3597</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU2LFDEQhoMo7rj6BzwsA6K3bqs6nU4CsiCLXzCgsus5pJPqJW1Pek1mhPn3ppmBgT14qsvz1sdTjL1GqBGwez_Wo3WubgC6GnQNon3CViiEqrjQ8ilbgeSiQtDygr3IeYQCKtTP2QVK3mqlYcWuNnO8X_-8W98eok_zltY2-vWPRPfRRnd4yZ4Ndsr06lQv2a_Pn-5uvlab71--3XzcVE60clf1EnrntVNSN7q1vW64aJFzi-hIyUFQC55kA52XnRTKO0E9RyIaSA-955fs3bHvQ5r_7CnvzDZkR9NkI837bCQ0olEIBXzzCBznfYplN4MCOlSikwvVHCmX5pwTDeYhha1NB4NgFndmNIs7s7gzoE1xV0JXp9b7fkv-HDnJKsDbE2Czs9OQiqGQz5wSSgHown04clSM_Q2UTHaBoiMfErmd8XP4_x7Xj-JuCjGUib_pQPl8r8mNAXO7fHl5MnTAEVXL_wHtu56S</recordid><startdate>20070313</startdate><enddate>20070313</enddate><creator>Seth, Rahul, MD</creator><creator>Moss, Arthur J., MD</creator><creator>McNitt, Scott, MS</creator><creator>Zareba, Wojciech, MD, PhD</creator><creator>Andrews, Mark L., BBA</creator><creator>Qi, Ming, PhD</creator><creator>Robinson, Jennifer L., MS</creator><creator>Goldenberg, Ilan, MD</creator><creator>Ackerman, Michael J., MD, PhD</creator><creator>Benhorin, Jesaia, MD</creator><creator>Kaufman, Elizabeth S., MD</creator><creator>Locati, Emanuela H., MD, PhD</creator><creator>Napolitano, Carlo, MD</creator><creator>Priori, Silvia G., MD, PhD</creator><creator>Schwartz, Peter J., MD</creator><creator>Towbin, Jeffrey A., MD</creator><creator>Vincent, G. 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Vascular system</topic><topic>Cardiovascular</topic><topic>Cohort Studies</topic><topic>Confidence Intervals</topic><topic>Death, Sudden, Cardiac - epidemiology</topic><topic>Death, Sudden, Cardiac - etiology</topic><topic>Drug therapy</topic><topic>Electrocardiography</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Genotype & phenotype</topic><topic>Gestational Age</topic><topic>Heart</topic><topic>Heart Arrest - mortality</topic><topic>Heart attacks</topic><topic>Heart rate</topic><topic>Humans</topic><topic>Internal Medicine</topic><topic>Long QT syndrome</topic><topic>Long QT Syndrome - diagnosis</topic><topic>Long QT Syndrome - mortality</topic><topic>Medical sciences</topic><topic>Mutation</topic><topic>Older people</topic><topic>Parity</topic><topic>Population</topic><topic>Postpartum Period</topic><topic>Pregnancy</topic><topic>Pregnancy Complications, Cardiovascular - diagnosis</topic><topic>Pregnancy Complications, Cardiovascular - mortality</topic><topic>Pregnancy Outcome</topic><topic>Pregnancy, High-Risk</topic><topic>Probability</topic><topic>Proportional Hazards Models</topic><topic>Ratios</topic><topic>Registries</topic><topic>Retrospective Studies</topic><topic>Risk Assessment</topic><topic>Studies</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Seth, Rahul, MD</creatorcontrib><creatorcontrib>Moss, Arthur J., MD</creatorcontrib><creatorcontrib>McNitt, Scott, MS</creatorcontrib><creatorcontrib>Zareba, Wojciech, MD, PhD</creatorcontrib><creatorcontrib>Andrews, Mark L., BBA</creatorcontrib><creatorcontrib>Qi, Ming, PhD</creatorcontrib><creatorcontrib>Robinson, Jennifer L., MS</creatorcontrib><creatorcontrib>Goldenberg, Ilan, MD</creatorcontrib><creatorcontrib>Ackerman, Michael J., MD, PhD</creatorcontrib><creatorcontrib>Benhorin, Jesaia, MD</creatorcontrib><creatorcontrib>Kaufman, Elizabeth S., MD</creatorcontrib><creatorcontrib>Locati, Emanuela H., MD, PhD</creatorcontrib><creatorcontrib>Napolitano, Carlo, MD</creatorcontrib><creatorcontrib>Priori, Silvia G., MD, PhD</creatorcontrib><creatorcontrib>Schwartz, Peter J., MD</creatorcontrib><creatorcontrib>Towbin, Jeffrey A., MD</creatorcontrib><creatorcontrib>Vincent, G. Michael, MD</creatorcontrib><creatorcontrib>Zhang, Li, MD</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the American College of Cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Seth, Rahul, MD</au><au>Moss, Arthur J., MD</au><au>McNitt, Scott, MS</au><au>Zareba, Wojciech, MD, PhD</au><au>Andrews, Mark L., BBA</au><au>Qi, Ming, PhD</au><au>Robinson, Jennifer L., MS</au><au>Goldenberg, Ilan, MD</au><au>Ackerman, Michael J., MD, PhD</au><au>Benhorin, Jesaia, MD</au><au>Kaufman, Elizabeth S., MD</au><au>Locati, Emanuela H., MD, PhD</au><au>Napolitano, Carlo, MD</au><au>Priori, Silvia G., MD, PhD</au><au>Schwartz, Peter J., MD</au><au>Towbin, Jeffrey A., MD</au><au>Vincent, G. Michael, MD</au><au>Zhang, Li, MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Long QT Syndrome and Pregnancy</atitle><jtitle>Journal of the American College of Cardiology</jtitle><addtitle>J Am Coll Cardiol</addtitle><date>2007-03-13</date><risdate>2007</risdate><volume>49</volume><issue>10</issue><spage>1092</spage><epage>1098</epage><pages>1092-1098</pages><issn>0735-1097</issn><eissn>1558-3597</eissn><coden>JACCDI</coden><abstract>Long QT Syndrome and Pregnancy Rahul Seth, Arthur J. Moss, Scott McNitt, Wojciech Zareba, Mark L. Andrews, Ming Qi, Jennifer L. Robinson, Ilan Goldenberg, Michael J. Ackerman, Jesaia Benhorin, Elizabeth S. Kaufman, Emanuela H. Locati, Carlo Napolitano, Silvia G. Priori, Peter J. Schwartz, Jeffrey A. Towbin, G. Michael Vincent, Li Zhang The risk of experiencing an adverse cardiac event, including syncope, aborted cardiac arrest, and sudden death, during and after pregnancy was analyzed for women who had their first birth from 1980 to 2003 (n = 391). Compared with a time period before a woman’s first conception, the pregnancy time was associated with a reduced risk of cardiac events and an increased risk during the 9-month postpartum period, especially among women with the LQT2 genotype. Beta-blockers were associated with a reduction in cardiac events during the high-risk postpartum time period.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>17349890</pmid><doi>10.1016/j.jacc.2006.09.054</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Abortion Adult Age Biological and medical sciences Births Cardiac dysrhythmias Cardiology Cardiology. Vascular system Cardiovascular Cohort Studies Confidence Intervals Death, Sudden, Cardiac - epidemiology Death, Sudden, Cardiac - etiology Drug therapy Electrocardiography Female Follow-Up Studies Genotype & phenotype Gestational Age Heart Heart Arrest - mortality Heart attacks Heart rate Humans Internal Medicine Long QT syndrome Long QT Syndrome - diagnosis Long QT Syndrome - mortality Medical sciences Mutation Older people Parity Population Postpartum Period Pregnancy Pregnancy Complications, Cardiovascular - diagnosis Pregnancy Complications, Cardiovascular - mortality Pregnancy Outcome Pregnancy, High-Risk Probability Proportional Hazards Models Ratios Registries Retrospective Studies Risk Assessment Studies Womens health |
title | Long QT Syndrome and Pregnancy |
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