Long QT Syndrome and Pregnancy

Long QT Syndrome and Pregnancy Rahul Seth, Arthur J. Moss, Scott McNitt, Wojciech Zareba, Mark L. Andrews, Ming Qi, Jennifer L. Robinson, Ilan Goldenberg, Michael J. Ackerman, Jesaia Benhorin, Elizabeth S. Kaufman, Emanuela H. Locati, Carlo Napolitano, Silvia G. Priori, Peter J. Schwartz, Jeffrey A....

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Veröffentlicht in:Journal of the American College of Cardiology 2007-03, Vol.49 (10), p.1092-1098
Hauptverfasser: Seth, Rahul, MD, Moss, Arthur J., MD, McNitt, Scott, MS, Zareba, Wojciech, MD, PhD, Andrews, Mark L., BBA, Qi, Ming, PhD, Robinson, Jennifer L., MS, Goldenberg, Ilan, MD, Ackerman, Michael J., MD, PhD, Benhorin, Jesaia, MD, Kaufman, Elizabeth S., MD, Locati, Emanuela H., MD, PhD, Napolitano, Carlo, MD, Priori, Silvia G., MD, PhD, Schwartz, Peter J., MD, Towbin, Jeffrey A., MD, Vincent, G. Michael, MD, Zhang, Li, MD
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container_end_page 1098
container_issue 10
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container_title Journal of the American College of Cardiology
container_volume 49
creator Seth, Rahul, MD
Moss, Arthur J., MD
McNitt, Scott, MS
Zareba, Wojciech, MD, PhD
Andrews, Mark L., BBA
Qi, Ming, PhD
Robinson, Jennifer L., MS
Goldenberg, Ilan, MD
Ackerman, Michael J., MD, PhD
Benhorin, Jesaia, MD
Kaufman, Elizabeth S., MD
Locati, Emanuela H., MD, PhD
Napolitano, Carlo, MD
Priori, Silvia G., MD, PhD
Schwartz, Peter J., MD
Towbin, Jeffrey A., MD
Vincent, G. Michael, MD
Zhang, Li, MD
description Long QT Syndrome and Pregnancy Rahul Seth, Arthur J. Moss, Scott McNitt, Wojciech Zareba, Mark L. Andrews, Ming Qi, Jennifer L. Robinson, Ilan Goldenberg, Michael J. Ackerman, Jesaia Benhorin, Elizabeth S. Kaufman, Emanuela H. Locati, Carlo Napolitano, Silvia G. Priori, Peter J. Schwartz, Jeffrey A. Towbin, G. Michael Vincent, Li Zhang The risk of experiencing an adverse cardiac event, including syncope, aborted cardiac arrest, and sudden death, during and after pregnancy was analyzed for women who had their first birth from 1980 to 2003 (n = 391). Compared with a time period before a woman’s first conception, the pregnancy time was associated with a reduced risk of cardiac events and an increased risk during the 9-month postpartum period, especially among women with the LQT2 genotype. Beta-blockers were associated with a reduction in cardiac events during the high-risk postpartum time period.
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Michael Vincent, Li Zhang The risk of experiencing an adverse cardiac event, including syncope, aborted cardiac arrest, and sudden death, during and after pregnancy was analyzed for women who had their first birth from 1980 to 2003 (n = 391). Compared with a time period before a woman’s first conception, the pregnancy time was associated with a reduced risk of cardiac events and an increased risk during the 9-month postpartum period, especially among women with the LQT2 genotype. Beta-blockers were associated with a reduction in cardiac events during the high-risk postpartum time period.</description><identifier>ISSN: 0735-1097</identifier><identifier>EISSN: 1558-3597</identifier><identifier>DOI: 10.1016/j.jacc.2006.09.054</identifier><identifier>PMID: 17349890</identifier><identifier>CODEN: JACCDI</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Abortion ; Adult ; Age ; Biological and medical sciences ; Births ; Cardiac dysrhythmias ; Cardiology ; Cardiology. 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Michael, MD</creatorcontrib><creatorcontrib>Zhang, Li, MD</creatorcontrib><title>Long QT Syndrome and Pregnancy</title><title>Journal of the American College of Cardiology</title><addtitle>J Am Coll Cardiol</addtitle><description>Long QT Syndrome and Pregnancy Rahul Seth, Arthur J. Moss, Scott McNitt, Wojciech Zareba, Mark L. Andrews, Ming Qi, Jennifer L. Robinson, Ilan Goldenberg, Michael J. Ackerman, Jesaia Benhorin, Elizabeth S. Kaufman, Emanuela H. Locati, Carlo Napolitano, Silvia G. Priori, Peter J. Schwartz, Jeffrey A. Towbin, G. Michael Vincent, Li Zhang The risk of experiencing an adverse cardiac event, including syncope, aborted cardiac arrest, and sudden death, during and after pregnancy was analyzed for women who had their first birth from 1980 to 2003 (n = 391). Compared with a time period before a woman’s first conception, the pregnancy time was associated with a reduced risk of cardiac events and an increased risk during the 9-month postpartum period, especially among women with the LQT2 genotype. Beta-blockers were associated with a reduction in cardiac events during the high-risk postpartum time period.</description><subject>Abortion</subject><subject>Adult</subject><subject>Age</subject><subject>Biological and medical sciences</subject><subject>Births</subject><subject>Cardiac dysrhythmias</subject><subject>Cardiology</subject><subject>Cardiology. Vascular system</subject><subject>Cardiovascular</subject><subject>Cohort Studies</subject><subject>Confidence Intervals</subject><subject>Death, Sudden, Cardiac - epidemiology</subject><subject>Death, Sudden, Cardiac - etiology</subject><subject>Drug therapy</subject><subject>Electrocardiography</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Genotype &amp; phenotype</subject><subject>Gestational Age</subject><subject>Heart</subject><subject>Heart Arrest - mortality</subject><subject>Heart attacks</subject><subject>Heart rate</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Long QT syndrome</subject><subject>Long QT Syndrome - diagnosis</subject><subject>Long QT Syndrome - mortality</subject><subject>Medical sciences</subject><subject>Mutation</subject><subject>Older people</subject><subject>Parity</subject><subject>Population</subject><subject>Postpartum Period</subject><subject>Pregnancy</subject><subject>Pregnancy Complications, Cardiovascular - diagnosis</subject><subject>Pregnancy Complications, Cardiovascular - mortality</subject><subject>Pregnancy Outcome</subject><subject>Pregnancy, High-Risk</subject><subject>Probability</subject><subject>Proportional Hazards Models</subject><subject>Ratios</subject><subject>Registries</subject><subject>Retrospective Studies</subject><subject>Risk Assessment</subject><subject>Studies</subject><subject>Womens health</subject><issn>0735-1097</issn><issn>1558-3597</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU2LFDEQhoMo7rj6BzwsA6K3bqs6nU4CsiCLXzCgsus5pJPqJW1Pek1mhPn3ppmBgT14qsvz1sdTjL1GqBGwez_Wo3WubgC6GnQNon3CViiEqrjQ8ilbgeSiQtDygr3IeYQCKtTP2QVK3mqlYcWuNnO8X_-8W98eok_zltY2-vWPRPfRRnd4yZ4Ndsr06lQv2a_Pn-5uvlab71--3XzcVE60clf1EnrntVNSN7q1vW64aJFzi-hIyUFQC55kA52XnRTKO0E9RyIaSA-955fs3bHvQ5r_7CnvzDZkR9NkI837bCQ0olEIBXzzCBznfYplN4MCOlSikwvVHCmX5pwTDeYhha1NB4NgFndmNIs7s7gzoE1xV0JXp9b7fkv-HDnJKsDbE2Czs9OQiqGQz5wSSgHown04clSM_Q2UTHaBoiMfErmd8XP4_x7Xj-JuCjGUib_pQPl8r8mNAXO7fHl5MnTAEVXL_wHtu56S</recordid><startdate>20070313</startdate><enddate>20070313</enddate><creator>Seth, Rahul, MD</creator><creator>Moss, Arthur J., MD</creator><creator>McNitt, Scott, MS</creator><creator>Zareba, Wojciech, MD, PhD</creator><creator>Andrews, Mark L., BBA</creator><creator>Qi, Ming, PhD</creator><creator>Robinson, Jennifer L., MS</creator><creator>Goldenberg, Ilan, MD</creator><creator>Ackerman, Michael J., MD, PhD</creator><creator>Benhorin, Jesaia, MD</creator><creator>Kaufman, Elizabeth S., MD</creator><creator>Locati, Emanuela H., MD, PhD</creator><creator>Napolitano, Carlo, MD</creator><creator>Priori, Silvia G., MD, PhD</creator><creator>Schwartz, Peter J., MD</creator><creator>Towbin, Jeffrey A., MD</creator><creator>Vincent, G. 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Michael Vincent, Li Zhang The risk of experiencing an adverse cardiac event, including syncope, aborted cardiac arrest, and sudden death, during and after pregnancy was analyzed for women who had their first birth from 1980 to 2003 (n = 391). Compared with a time period before a woman’s first conception, the pregnancy time was associated with a reduced risk of cardiac events and an increased risk during the 9-month postpartum period, especially among women with the LQT2 genotype. Beta-blockers were associated with a reduction in cardiac events during the high-risk postpartum time period.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>17349890</pmid><doi>10.1016/j.jacc.2006.09.054</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record>
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subjects Abortion
Adult
Age
Biological and medical sciences
Births
Cardiac dysrhythmias
Cardiology
Cardiology. Vascular system
Cardiovascular
Cohort Studies
Confidence Intervals
Death, Sudden, Cardiac - epidemiology
Death, Sudden, Cardiac - etiology
Drug therapy
Electrocardiography
Female
Follow-Up Studies
Genotype & phenotype
Gestational Age
Heart
Heart Arrest - mortality
Heart attacks
Heart rate
Humans
Internal Medicine
Long QT syndrome
Long QT Syndrome - diagnosis
Long QT Syndrome - mortality
Medical sciences
Mutation
Older people
Parity
Population
Postpartum Period
Pregnancy
Pregnancy Complications, Cardiovascular - diagnosis
Pregnancy Complications, Cardiovascular - mortality
Pregnancy Outcome
Pregnancy, High-Risk
Probability
Proportional Hazards Models
Ratios
Registries
Retrospective Studies
Risk Assessment
Studies
Womens health
title Long QT Syndrome and Pregnancy
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