Long QT Syndrome and Pregnancy

Long QT Syndrome and Pregnancy Rahul Seth, Arthur J. Moss, Scott McNitt, Wojciech Zareba, Mark L. Andrews, Ming Qi, Jennifer L. Robinson, Ilan Goldenberg, Michael J. Ackerman, Jesaia Benhorin, Elizabeth S. Kaufman, Emanuela H. Locati, Carlo Napolitano, Silvia G. Priori, Peter J. Schwartz, Jeffrey A....

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Veröffentlicht in:	Journal of the American College of Cardiology 2007-03, Vol.49 (10), p.1092-1098
Hauptverfasser:	Seth, Rahul, MD, Moss, Arthur J., MD, McNitt, Scott, MS, Zareba, Wojciech, MD, PhD, Andrews, Mark L., BBA, Qi, Ming, PhD, Robinson, Jennifer L., MS, Goldenberg, Ilan, MD, Ackerman, Michael J., MD, PhD, Benhorin, Jesaia, MD, Kaufman, Elizabeth S., MD, Locati, Emanuela H., MD, PhD, Napolitano, Carlo, MD, Priori, Silvia G., MD, PhD, Schwartz, Peter J., MD, Towbin, Jeffrey A., MD, Vincent, G. Michael, MD, Zhang, Li, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Abortion Adult Age Biological and medical sciences Births Cardiac dysrhythmias Cardiology Cardiology. Vascular system Cardiovascular Cohort Studies Confidence Intervals Death, Sudden, Cardiac - epidemiology Death, Sudden, Cardiac - etiology Drug therapy Electrocardiography Female Follow-Up Studies Genotype & phenotype Gestational Age Heart Heart Arrest - mortality Heart attacks Heart rate Humans Internal Medicine Long QT syndrome Long QT Syndrome - diagnosis Long QT Syndrome - mortality Medical sciences Mutation Older people Parity Population Postpartum Period Pregnancy Pregnancy Complications, Cardiovascular - diagnosis Pregnancy Complications, Cardiovascular - mortality Pregnancy Outcome Pregnancy, High-Risk Probability Proportional Hazards Models Ratios Registries Retrospective Studies Risk Assessment Studies Womens health
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Zusammenfassung:	Long QT Syndrome and Pregnancy Rahul Seth, Arthur J. Moss, Scott McNitt, Wojciech Zareba, Mark L. Andrews, Ming Qi, Jennifer L. Robinson, Ilan Goldenberg, Michael J. Ackerman, Jesaia Benhorin, Elizabeth S. Kaufman, Emanuela H. Locati, Carlo Napolitano, Silvia G. Priori, Peter J. Schwartz, Jeffrey A. Towbin, G. Michael Vincent, Li Zhang The risk of experiencing an adverse cardiac event, including syncope, aborted cardiac arrest, and sudden death, during and after pregnancy was analyzed for women who had their first birth from 1980 to 2003 (n = 391). Compared with a time period before a woman’s first conception, the pregnancy time was associated with a reduced risk of cardiac events and an increased risk during the 9-month postpartum period, especially among women with the LQT2 genotype. Beta-blockers were associated with a reduction in cardiac events during the high-risk postpartum time period.
ISSN:	0735-1097 1558-3597
DOI:	10.1016/j.jacc.2006.09.054