Using coupled monolithic rods for ultra-high peak capacity LC and LC-MS under normal LC operating pressures
Up to ten individual reversed-phase monolithic LC columns were efficiently coupled to equal a total column length of 1 m. The column generated up to 90,000 theoretical plates under optimum conditions with a peak capacity under gradient conditions of 244 peaks h(-1) at a total column backpressure of...
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| Veröffentlicht in: | Analyst (London) 2008-02, Vol.133 (2), p.180-183 |
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| container_title | Analyst (London) |
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| creator | BONES, Jonathan DUFFY, Cepta MACKA, Mirek PAULL, Brett |
| description | Up to ten individual reversed-phase monolithic LC columns were efficiently coupled to equal a total column length of 1 m. The column generated up to 90,000 theoretical plates under optimum conditions with a peak capacity under gradient conditions of 244 peaks h(-1) at a total column backpressure of just 140 bar, directly coupled to ESI-MS. |
| doi_str_mv | 10.1039/b714807k |
| format | Article |
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| identifier | ISSN: 0003-2654 |
| ispartof | Analyst (London), 2008-02, Vol.133 (2), p.180-183 |
| issn | 0003-2654 1364-5528 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_70238035 |
| source | MEDLINE; Royal Society Of Chemistry Journals; Royal Society of Chemistry Journals Archive (1841-2007); Alma/SFX Local Collection |
| subjects | Analytical chemistry Animals Chemistry Chromatographic methods and physical methods associated with chromatography Chromatography, Liquid - instrumentation Chromatography, Liquid - methods Exact sciences and technology Humans Other chromatographic methods Proteins - analysis Sensitivity and Specificity Spectrometric and optical methods Spectrometry, Mass, Electrospray Ionization - methods |
| title | Using coupled monolithic rods for ultra-high peak capacity LC and LC-MS under normal LC operating pressures |
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