Chitohexose Induce the Yeast Proliferation of Candida albicans

Candida albicans generally grows in the hyphae form in RPMI1640 medium. Chitohexose (COS-6) induced the yeast form of C. albicans dose-dependently under this condition. When COS-6 was exposed to C. albicans, yeast proliferation was observed 6 h after starting the incubation. When we observed the gro...

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Veröffentlicht in:	Biological & Pharmaceutical Bulletin 2007, Vol.30(3), pp.583-584
Hauptverfasser:	Kadowaki, Osamu, Ogasawara, Ayako, Watanabe, Toshihiko, Mikami, Takeshi, Matsumoto, Tatsuji, Misawa, Yoshitomo, Matahira, Yoshiharu, Sakai, Kazuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Candida albicans Candida albicans - cytology Candida albicans - drug effects Candida albicans - growth & development Cell Division - drug effects chitohexose Colony Count, Microbial - methods Dose-Response Relationship, Drug hyphae morphological change Oligosaccharides - pharmacology Time Factors yeast
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Zusammenfassung:	Candida albicans generally grows in the hyphae form in RPMI1640 medium. Chitohexose (COS-6) induced the yeast form of C. albicans dose-dependently under this condition. When COS-6 was exposed to C. albicans, yeast proliferation was observed 6 h after starting the incubation. When we observed the growth form of C. albicans cultured with COS-6, yeast proliferation was observed at log-phase. These results showed that COS-6 was useful for the yeast form inducer of C. albicans.
ISSN:	0918-6158 1347-5215
DOI:	10.1248/bpb.30.583