Paramutation: From Maize to Mice

Paramutation: From Maize to Mice

Paramutation is the epigenetic transfer of information from one allele of a gene to another to establish a state of gene expression that is heritable for generations. RNA has recently emerged as a prominent mediator of this remarkable phenomenon in both maize and mice.

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Bibliographische Detailangaben
Veröffentlicht in:Cell 2007-02, Vol.128 (4), p.641-645
1. Verfasser: Chandler, Vicki L.
Format: Artikel
Sprache:eng
Schlagworte:
Alleles
Animals
Epigenesis, Genetic - genetics
Gene Expression Regulation - genetics
Heredity
Humans
Mice
Mutation - genetics
RNA - genetics
Zea mays
Zea mays - genetics
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Beschreibung
Zusammenfassung:Paramutation is the epigenetic transfer of information from one allele of a gene to another to establish a state of gene expression that is heritable for generations. RNA has recently emerged as a prominent mediator of this remarkable phenomenon in both maize and mice.
ISSN:0092-8674
1097-4172
DOI:10.1016/j.cell.2007.02.007