A- seco-oleane-type triterpenes from Phomopsis sp. (strain HKI0458) isolated from the mangrove plant Hibiscus tiliaceus

A- seco-oleane-type triterpenes (1–4) were isolated from the fermentation broth of a fungus Phomopsis sp. (HKI0458), which was isolated from the mangrove plant Hibiscus tiliaceus (L.). Their structures were elucidated by extensive spectroscopic data analyses. From the fermentation broth of an unidentified Phomopsis sp. (strain HKI0458) isolated from the mangrove plant Hibiscus tiliaceus, four A- seco-oleane-type triterpenes, namely 3,4- seco-olean-11,13-dien-4,15α, 22β,24-tetraol-3-oic acid ( 1), 3,4- seco-olean-11,13-dien-4,7β,22β,24-tetraol-3-oic acid ( 2), 3,4- seco- olean-13-en-4,7,15,22,24-pentaol-3-oic acid ( 3), and 3,4- seco-olean-13-en-4,15,22,24-tetraol-3-oic acid ( 4) were obtained. Their structures were elucidated by extensive spectroscopic (UV, IR, FABMS, and 2D NMR) data analyses.