Substituted indanylacetic acids as PPAR-α–γ activators
A series of substituted indanylacetic acids were prepared which showed a spectrum of agonist activity against PPAR nuclear receptor subtypes. A series of oxazole-substituted indanylacetic acids were prepared which show a spectrum of activity as ligands for PPAR nuclear receptor subtypes.
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Veröffentlicht in: | Bioorganic & medicinal chemistry letters 2006-01, Vol.16 (2), p.297-301 |
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Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | A series of substituted indanylacetic acids were prepared which showed a spectrum of agonist activity against PPAR nuclear receptor subtypes.
A series of oxazole-substituted indanylacetic acids were prepared which show a spectrum of activity as ligands for PPAR nuclear receptor subtypes. |
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ISSN: | 0960-894X 1464-3405 |
DOI: | 10.1016/j.bmcl.2005.10.008 |