Next-generation sequencing transforms today's biology

A new generation of non-Sanger-based sequencing technologies has delivered on its promise of sequencing DNA at unprecedented speed, thereby enabling impressive scientific achievements and novel biological applications. However, before stepping into the limelight, next-generation sequencing had to ov...

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Veröffentlicht in:	Nature methods 2008-01, Vol.5 (1), p.16-18
1. Verfasser:	Schuster, Stephan C
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Bioinformatics Biological Microscopy Biological Techniques Biology - trends Biomedical and Life Sciences Biomedical Engineering/Biotechnology commentary Deoxyribonucleic acid DNA DNA sequencing Forecasting Genomics Life Sciences Methods Nucleotide sequence Nucleotide sequencing Oligonucleotide Array Sequence Analysis - trends Proteomics Research methodology Sequence Analysis, DNA - trends Technological change
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Beschreibung
Zusammenfassung:	A new generation of non-Sanger-based sequencing technologies has delivered on its promise of sequencing DNA at unprecedented speed, thereby enabling impressive scientific achievements and novel biological applications. However, before stepping into the limelight, next-generation sequencing had to overcome the inertia of a field that relied on Sanger-sequencing for 30 years.
ISSN:	1548-7091 1548-7105
DOI:	10.1038/nmeth1156