Microparticle-enhanced cultivation of filamentous microorganisms: Increased chloroperoxidase formation by Caldariomyces fumago as an example

Microparticle-enhanced cultivation (MPEC) was applied as a novel method for improved biomass and product formation during cultivation of filamentous microorganisms. Exemplarily, chloroperoxidase (CPO) formation by Caldariomyces fumago was analyzed in the presence and absence of microparticles of dif...

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Veröffentlicht in:	Biotechnology and bioengineering 2008-02, Vol.99 (3), p.491-498
Hauptverfasser:	Kaup, Bjoern-Arne, Ehrich, Kristina, Pescheck, Michael, Schrader, Jens
Format:	Artikel
Sprache:	eng
Schlagworte:	Ascomycota - enzymology Ascomycota - growth & development Biological and medical sciences Bioreactors - microbiology Biotechnology Caldariomyces fumago Cell culture Cell Culture Techniques - methods Cell growth Cell Proliferation Cell Survival Chloride Peroxidase - metabolism chloroperoxidase cultivation filamentous microorganisms Fundamental and applied biological sciences. Psychology Methods. Procedures. Technologies Microbial engineering. Fermentation and microbial culture technology Microorganisms microparticles Microspheres
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Zusammenfassung:	Microparticle-enhanced cultivation (MPEC) was applied as a novel method for improved biomass and product formation during cultivation of filamentous microorganisms. Exemplarily, chloroperoxidase (CPO) formation by Caldariomyces fumago was analyzed in the presence and absence of microparticles of different size. Particles of ~500 μm in diameter had no effect on growth morphology or productivity of CPO formation by C. fumago. In contrast particles of
ISSN:	0006-3592 1097-0290
DOI:	10.1002/bit.21713