Effect of Antecedent Hypertension and Follow-Up Blood Pressure on Outcomes After High-Risk Myocardial Infarction

The influence of blood pressure on outcomes after high-risk myocardial infarction is not well characterized. We studied the relationship between blood pressure and the risk of cardiovascular events in 14 703 patients with heart failure, left ventricular systolic dysfunction, or both after acute myoc...

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Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Tex. 1979), 2008-01, Vol.51 (1), p.48-54
Hauptverfasser:	Thune, Jens J, Signorovitch, James, Kober, Lars, Velazquez, Eric J, McMurray, John J.V, Califf, Robert M, Maggioni, Aldo P, Rouleau, Jean L, Howlett, Jonathan, Zelenkofske, Steven, Pfeffer, Marc A, Solomon, Scott D
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antihypertensive Agents - therapeutic use Blood Pressure - physiology Captopril - therapeutic use Cardiovascular Diseases - epidemiology Cardiovascular Diseases - physiopathology Female Follow-Up Studies Heart Failure - epidemiology Heart Failure - physiopathology Humans Hypertension - complications Hypertension - physiopathology Male Middle Aged Myocardial Infarction - complications Myocardial Infarction - physiopathology Prognosis Risk Factors Stroke - epidemiology Stroke - physiopathology Tetrazoles - therapeutic use Valine - analogs & derivatives Valine - therapeutic use Valsartan Ventricular Dysfunction, Left - complications Ventricular Dysfunction, Left - physiopathology
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Zusammenfassung:	The influence of blood pressure on outcomes after high-risk myocardial infarction is not well characterized. We studied the relationship between blood pressure and the risk of cardiovascular events in 14 703 patients with heart failure, left ventricular systolic dysfunction, or both after acute myocardial infarction in the Valsartan in Myocardial Infarction Trial. We assessed the relationship between antecedent hypertension and outcomes and the association between elevated (systolic>140 mm Hg) or low blood pressure (systolic
ISSN:	0194-911X 1524-4563
DOI:	10.1161/HYPERTENSIONAHA.107.093682