Effect of extracellular palmitate on 2-deoxy-D-glucose uptake in muscle from ad libitum fed and calorie restricted rats

We studied the effect of a high physiologic concentration of palmitate (1mM) on in vitro 2-deoxy-D-glucose (2DG) uptake by flexor digitorum brevis (FDB) muscle from ad libitum fed rats (AL) and rats fed 60% of ad libitum intake (CR) for 20 days. CR did not alter muscle 2DG uptake in the absence of i...

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Veröffentlicht in:	Biochemical and biophysical research communications 1998-11, Vol.252 (3), p.733-737
Hauptverfasser:	Gazdag, A.C, Tucker, M.Z, Turcotte, L.P, Dean, D.J, Cartee, G.D
Format:	Artikel
Sprache:	eng
Schlagworte:	ad libitum feeding Animals Blood Glucose - metabolism Body Weight carbohydrate metabolism Carrier Proteins - metabolism Cell Membrane - metabolism Deoxyglucose - pharmacokinetics Energy Intake Fatty Acid-Binding Protein 7 Fatty Acid-Binding Proteins Fatty Acids, Nonesterified - blood Fatty Acids, Nonesterified - pharmacology Food Deprivation Glucose - pharmacokinetics glucose metabolism Male Muscles - drug effects Muscles - metabolism Myelin P2 Protein - metabolism Neoplasm Proteins Nerve Tissue Proteins Palmitates - pharmacology Rats Rats, Inbred F344 restricted feeding skeletal muscle
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Zusammenfassung:	We studied the effect of a high physiologic concentration of palmitate (1mM) on in vitro 2-deoxy-D-glucose (2DG) uptake by flexor digitorum brevis (FDB) muscle from ad libitum fed rats (AL) and rats fed 60% of ad libitum intake (CR) for 20 days. CR did not alter muscle 2DG uptake in the absence of insulin, but relative to AL, CR significantly (p
ISSN:	0006-291X 1090-2104
DOI:	10.1006/bbrc.1998.9713