Methods for selection of aptamers to protein targets

Aptamers are synthetic single-stranded RNA or DNA molecules capable of specific binding to other target molecules. In this review, the main aptamer properties are considered and methods for selection of aptamers against various protein targets are described. Special attention is given to the methods...

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Veröffentlicht in:	Biochemistry (Moscow) 2007-12, Vol.72 (13), p.1505-1518
1. Verfasser:	Kulbachinskiy, A V
Format:	Artikel
Sprache:	eng
Schlagworte:	Aptamers, Nucleotide - chemistry Combinatorial Chemistry Techniques Deoxyribonucleic acid DNA DNA, Single-Stranded - chemistry Epitopes Gene Library Genetic Techniques Ligands Methods Oligonucleotides - chemistry Proteins Proteins - chemistry RNA - chemistry Selection, Genetic SELEX Aptamer Technique - methods
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