L-proline as a nitrogen source increases the susceptibility of Saccharomyces cerevisiae S288c to fluconazole

Fluconazole inhibition of Saccharomyces cerevisiae S288c growth was evaluated in media containing ammonia, L-proline or L-leucine as a nitrogen source. Growth inhibition by fluconazole was maximum when L-proline was used as a nitrogen source, while rhodamine 6G accumulation and fluconazole resistanc...

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Veröffentlicht in:Folia microbiologica 1998, Vol.43 (4), p.403-405
Hauptverfasser: STELLA, C, COSTANZO, R, BURGOS, H. I, SAENZ, D, VENERUS, R. D
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container_title Folia microbiologica
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creator STELLA, C
COSTANZO, R
BURGOS, H. I
SAENZ, D
VENERUS, R. D
description Fluconazole inhibition of Saccharomyces cerevisiae S288c growth was evaluated in media containing ammonia, L-proline or L-leucine as a nitrogen source. Growth inhibition by fluconazole was maximum when L-proline was used as a nitrogen source, while rhodamine 6G accumulation and fluconazole resistance were the highest when ammonia was the sole nitrogen source.
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subjects Antibiotics. Antiinfectious agents. Antiparasitic agents
Antifungal agents
Antifungal Agents - pharmacology
Biological and medical sciences
Culture Media
Drug Resistance, Microbial
Fluconazole - pharmacology
Medical sciences
Microbial Sensitivity Tests
Nitrogen - metabolism
Pharmacology. Drug treatments
Proline - metabolism
Rhodamines - metabolism
Saccharomyces cerevisiae
Saccharomyces cerevisiae - drug effects
Saccharomyces cerevisiae - growth & development
title L-proline as a nitrogen source increases the susceptibility of Saccharomyces cerevisiae S288c to fluconazole
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